An equivalent source method for acoustic problems with thermoviscous effects.

This paper presents an equivalent source method (ESM) for analyzing sound propagation in small-scale acoustic structures with thermoviscous effects. The formulations that describe the thermal, viscous, and acoustic modes for thermoviscous acoustic problems are introduced. The concept of ESM is then applied to solve these formulations, resulting in an efficient numerical computation and implementation procedure.

Analytical method for studying acoustic fields radiated by general spherical sound sources in thermoviscous fluids.

The study of acoustic radiation from spherical sound sources plays a crucial role in understanding the thermoviscous effects in practical acoustic problems. However, finding a general solution of acoustic radiation from spherical sound sources in thermoviscous fluids remains a formidable challenge. To advance this issue, an analytical method is developed in this paper to calculate the acoustic field radiated by spherical sound sources with the isothermal boundary condition and arbitrary velocity boundary condition.

Designing a sparse sensor array for sound field reconstruction using compressive-equivalent source method.

The compressive-equivalent source method (C-ESM) can reconstruct the sound field radiated by sparsely distributed sound sources with a reduced number of sensors. To ensure the performance of the C-ESM, the transfer matrix between the sensors and equivalent point sources should exhibit sufficient incoherence. Given that the configuration of the sensor array affects this incoherence condition, concern regarding the sensor array design would arise.

Repairing distorted hologram data for sound field reconstruction.

This paper proposes a distorted hologram data repair approach for sound field reconstruction. In this approach, an equivalent source model is established by placing a set of equivalent sources near the hologram surface to represent the measured hologram pressures. Each hologram pressure is simultaneously assigned an indicator to describe whether its measurement is corrupted by errors or not.

Real-time nearfield acoustic holography using particle velocity.

In this paper, a series of impulse response functions between acoustic quantities on the source plane and particle velocity on the hologram plane are derived. In virtue of these functions, real-time nearfield acoustic holography (RT-NAH) is extended from pressure-based to particle velocity. Pressure, normal velocity, acceleration, and displacement radiated from planar sources can be reconstructed by measuring time-dependent particle velocity signals on the hologram plane.

The safety and efficacy of neoadjuvant immunochemotherapy following laparoscopic gastrectomy for gastric cancer: a multicentre real-world clinical study.

Background: The safety and efficacy of neoadjuvant immunochemotherapy (nICT) for locally advanced gastric cancer (LAGC) remain controversial.

Methods: Patients with LAGC who received either nICT or neoadjuvant chemotherapy (nCT) at 3 tertiary referral teaching hospitals in China between January 2016 and October 2022 were analyzed. After propensity-score matching (PSM), comparing the radiological response, pathological response rate, perioperative outcomes, and early recurrence between the two groups.

Sound field reconstruction using block sparse Bayesian learning equivalent source method.

Nearfield acoustic holography based on the compressed sensing theory can realize the accurate reconstruction of sound fields with fewer measurement points on the premise that an appropriate sparse basis is obtained. However, for different types of sound sources, the appropriate sparse bases are diverse and should be constructed elaborately. In this paper, a block sparse Bayesian learning (SBL) equivalent source method is proposed for realizing the reconstruction of the sound fields radiated by different types of sources, including the spatially sparse sources, the spatially extended sources, and the mixed ones of the above two, without the elaborate construction of the sparse basis.

Reconstruction of time-dependent forces acting on a vibrating structure from pressure measurements.

This paper proposes an approach to reconstruct the time-dependent forces acting on a vibrating structure from pressure measurements. In the approach, the pressures measured in the near field of the structure are related to the exciting forces at the reconstruction points by the transfer functions determined in an experimental way, whereupon the time-dependent forces can be reconstructed with these pressures as inputs. In the reconstruction process, an additional regularization with a mixed l -norm term is introduced to resolve the ill-posed inverse problem, which is able to take advantage of the prior knowledge of space and time characteristics of the forces.

Danggui-Shaoyao-San improves cognitive impairment through inhibiting O-GlcNAc-modification of estrogen α receptor in female db/db mice.

Ethnopharmacological Relevance: The traditional Chinese medicine formula Danggui-Shaoyao-San (DSS) has been reported to show therapeutic effect on dementia.

Aim Of The Study: The present study aims to investigate whether DSS treatment could alleviate diabetes-induced cognitive dysfunction, and explores its neuroprotective mechanism on db/db mice.

Materials And Methods: The female db/db mice were randomly divided into model group, DSS low-dose group and DSS high-dose group.

Separation of nonstationary sound fields based on the time-domain equivalent source method with single layer pressure-velocity measurements.

This paper proposes a sound field separation technique based on the time-domain equivalent source method with single layer pressure-velocity measurements to extract the nonstationary sound field radiated by the target source in a reverberant environment. This technique constructs a formulation that relates the pressures and particle velocities on a measurement surface to the strengths of time-domain equivalent sources arranged for modelling the outgoing and incoming waves. By solving the strengths of time-domain equivalent sources, the sounds coming from different sides of the measurement surface can be separated independently.

Reconstruction of nonstationary sound fields based on a time domain angular spectrum method.

A time domain angular spectrum method is proposed to reconstruct nonstationary sound fields. In this method, the sound field is expressed as a superposition of a series of plane wave bases, and the plane wave basis is constructed by an impulse response function that relates the time domain angular spectrum to the field point pressure. The impulse response function consists of two parts, the propagating plane waves and the evanescent plane waves, and their physical interpretation is provided.

A boundary element eigensolver for acoustic resonances in cavities with impedance boundary conditions.

This letter presents a boundary element scheme for analysis of acoustic resonances in cavities with impedance boundary conditions. The resultant eigenproblem, which is nonlinear and difficult to solve directly, is transformed to a linear one through a contour integral method. A variant-parameter scheme based on the Burton-Miller combined formulation is given to identify spurious eigenfrequencies, which are complex and similar to true eigenfrequencies.

Estimating the acoustical properties of locally reactive finite materials using the boundary element method.

The finite size of a sound-absorbing material may lead to inaccurate results when measuring the acoustical properties of the material using the free-field measurement methods. In this study, a method of estimating the acoustical properties of locally reactive finite materials is proposed by combining a sound field model established by the boundary element method with an iteration algorithm. The proposed method takes the finiteness of the material into account, meaning that the size effect is removed and accurate results can be obtained.

Identification of key candidate genes and pathways in anaplastic thyroid cancer by bioinformatics analysis.

Background: Anaplastic thyroid carcinoma (ATC) is a refractory and poor prognosis tumor Present study aimed to investigate the underlying biological functions and pathways involved in the development of ATC and to identify potential hub genes and candidate biomarkers of ATC.

Materials And Methods: Bioinformatics analyses were performed to identify the differentially expressed genes (DEGs) between ATC tissue samples and adjacent normal tissue samples. Protein-protein interaction (PPI) networks of the DEGs were constructed using Search Tool for the Retrieval of Interacting Genes online tool and Cytoscape software and divided into sub-networks using the Molecular Complex Detection (MCODE) plug-in.

On the stability of transient nearfield acoustic holography based on the time domain equivalent source method.

Transient nearfield acoustic holography based on the time domain equivalent source method suffers from the instability that is caused by the use of the time marching scheme. In this paper, the time marching scheme is reformulated to a large iterative scheme. By conducting the eigenanalysis of this large iterative scheme, a necessary condition for stability, i.

Sound field reconstruction using inverse boundary element method and sparse regularization.

The inverse boundary element method (IBEM) is a powerful tool for realizing sound field reconstruction of sources with arbitrarily-shaped surfaces. In the conventional IBEM, the Tikhonov regularization is generally used and the number of sampling points is required to be larger than that of nodes on the boundary surface to guarantee to obtain a unique solution. Meanwhile, it requires that the minimum discretization interval on the boundary surface should be less than one-sixth wavelength to ensure to obtain enough calculation accuracy.

Systems pharmacology-based investigation of Sanwei Ganjiang Prescription: related mechanisms in liver injury.

Liver injury remains a significant global health problem and has a variety of causes, including oxidative stress (OS), inflammation, and apoptosis of liver cells. There is currently no curative therapy for this disorder. Sanwei Ganjiang Prescription (SWGJP), derived from traditional Chinese medicine (TCM), has shown its effectiveness in long-term liver damage therapy, although the underlying molecular mechanisms are still not fully understood.

Ligustilide Ameliorates Memory Deficiency in APP/PS1 Transgenic Mice via Restoring Mitochondrial Dysfunction.

Ligustilide, the main lipophilic component of Radix angelicae sinensis, has been shown to ameliorate cognitive dysfunction in a few Alzheimer's disease mouse models, but its mechanism is not fully understood. In this study, we employed 7-month-old APP/PS1 mice to explore whether LIG is able to protect against Alzheimer's disease progression. The Morris water maze and Y-maze test results showed that eight weeks of intragastric administration of LIG (10 mg/kg, 40 mg/kg) every day improved memory deficit in APP/PS1 mice.

Stability analysis of inverse time domain boundary element method for near-field acoustic holography.

Stability of the inverse time domain boundary element method (ITBEM) for near-field acoustic holography is investigated. An eigenvalue system is built by reformulating the ITBEM to an iterative format. Through the analysis of the eigenvalue system, a stabilization criterion is derived.

Suppressing the onset of instabilities in the time-domain equivalent source method using a multistep approach.

Numerical instability is an important issue that should be addressed in the time-domain equivalent source method (TESM). This study proposes a multistep method to stabilize TESM when using the measured acoustic pressure data to optimize equivalent source strengths. Unlike the conventional single-step method that solves each time step in the time-marching process of TESM, the proposed method performs a one-time solution for several time steps.

A single pH fluorescent probe for biosensing and imaging of extreme acidity and extreme alkalinity.

A simple tailor-made pH fluorescent probe 2-benzothiazole (N-ethylcarbazole-3-yl) hydrazone (Probe) is facilely synthesized by the condensation reaction of 2-hydrazinobenzothiazole with N-ethylcarbazole-3-formaldehyde, which is a useful fluorescent probe for monitoring extremely acidic and alkaline pH, quantitatively. The pH titrations indicate that Probe displays a remarkable emission enhancement with a pK of 2.73 and responds linearly to minor pH fluctuations within the extremely acidic range of 2.

Sound field reconstruction using compressed modal equivalent point source method.

The accuracy, resolution, and economic cost of near-field acoustic holography (NAH) are highly dependent on the number of spatial sampling points. Generally, higher accuracy and resolution require more spatial sampling points, which may increase the workload of measurement or the hardware cost. Compressive sensing (CS) is able to solve the underdetermined problems by utilizing the sparsity of signals, and thus it can be applied to NAH to reduce the number of spatial sampling points but at the same time provide a high-resolution reconstruction image.

Coordination reactions of 2-pyridinecarboxaldehyde-phenylhydrazonatolithium with selected transition metal (Zn, Sn, Fe, Co, Ni and Zr) chlorides and its coupling reaction with dichloromethane.

The reactions of 2-pyridinecarboxaldehyde-phenylhydrazonatolithium C5H4Npy-CH[double bond, length as m-dash]Ni-NaLi(Ph) (abbreviated as Li) with a 1/2 equivalent of anhydrous metal (Zn, Sn, Fe and Co) chlorides or NiCl2(DME) (DME = 1, 2-dimethoxyethane) produced the corresponding mononuclear metal(ii) complexes ( and ), in which each ligand acts as a bidentate ligand and the coordination geometries around the metals are shown to be tetrahedral within the complexes , , and , respectively, and a tetragonal pyramid in the complex . The reaction of Li successively with sodium tert-butoxide and anhydrous ZrCl4 afforded the unanticipated bizirconium complex , in which each monoanionic ligand behaves as a tridentate bridge. Whereas treatment of Li with NiCl2 and then CH2Cl2 led to an interesting methylene-bridged bis(2-pyridyl-phenylhydrazone) compound in moderate yield; a comparative experiment showed that when the Li reacted with CH2Cl2, the coupling compound was also obtained but in very low yield.

Kegan Liyan oral liquid ameliorates lipopolysaccharide-induced acute lung injury through inhibition of TLR4-mediated NF-κB signaling pathway and MMP-9 expression.

Ethnopharmacological Relevance: Kegan Liyan oral liquid (KGLY), a Chinese prescription modified from classic formulas Yin-Qiao-San (from TCM classic Wenbing Tiaobian) and Shen-Jie-San (first mentioned in Shanghan Wenyi Tiaobian), has been reported to exert heat-clearing and detoxifying effects and used extensively for the treatment of severe pulmonary diseases in clinics including influenza, cough and pneumonia.

Aim Of This Study: The purpose of this study was to investigate the protective effect of KGLY on lipopolysaccharide (LPS) induced acute lung injury (ALI) in mice and to illuminate the underlying mechanisms.

Materials And Methods: Mice were orally administrated with KGLY (50, 100 and 150mg/kg) before intratracheal instillation of LPS.