Upregulation of a potential prognostic biomarker, miR-155, enhances cell proliferation in patients with oral squamous cell carcinoma.

Objective: We sought to investigate the role and diagnostic value of microRNA 155 (miR-155) in OSCC patients.

Study Design: Using real-time quantitative polymerase chain reaction analysis, miR-155 expression levels were assessed in OSCC cell lines and a cancerous HB cell line. The correlation between miR-155 expression level and clinical parameters was analyzed in 46 patients with OSCC.

Optimum post and tooth root diameters for a cast post-core system.

Purpose: To investigate the optimum diameter for the tapered post of a cast alloy post-core system relative to the root diameter, when measured at the root face, that is required to minimize both post and root failures.

Methods: 32 extracted maxillary central incisor teeth were each decoronated perpendicular to the long axis at a point 2.0 mm occlusal to the labial cemento-enamel junction.