Publications by authors named "Yong-Bao Li"

Purpose: The purpose of this study was to evaluate the performance of our quality assurance (QA) automation system and to evaluate the machine performance of a new type linear accelerator uRT-linac 506c within 6 months using this system.

Methods: This QA automation system consists of a hollow cylindrical phantom with 18 steel balls in the phantom surface and an analysis software to process electronic portal imaging device (EPID) measurement image data and report the results. The performance of the QA automation system was evaluated by the tests of repeatability, archivable precision, detectability of introduced errors, and the impact of set-up errors on QA results.

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Article Synopsis
  • IMRT can be time-intensive due to the manual adjustments needed for balancing dose delivery to the target and protecting nearby organs, making an automated optimization method desirable.
  • The proposed method automatically adjusts dose constraints based on clinical preferences to generate optimal solutions and incorporates a voxel weighting factor-based model for improved results.
  • Tests on cervical cancer cases showed that the automated method produced plans with the same target coverage but significantly reduced radiation exposure to the rectum and bladder compared to traditional methods.
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Objective: To establish the association between the geometric anatomical characteristics of the patients and the corresponding three-dimensional (3D) dose distribution of radiotherapy plan via feed-forward back-propagation neural network for clinical prediction of the plan dosimetric features.

Methods: A total of 25 fixed 13-field clinical prostate cancer intensity-modulated radiation therapy (IMRT)/stereotactic body radiation therapy (SBRT) plans were collected with a prescribed dose of 50 Gy. With the distance from each voxel to the planned target volume (PTV) boundary, the distance from each voxel to each organ-at-risk (OAR), and the volume of PTV as the geometric anatomical characteristics of the patients, the voxel deposition dose was used as the plan dosimetric feature.

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