Comparative Metabolic Profiling of Different Colored Rice Grains Reveals the Distribution of Major Active Compounds and Key Secondary Metabolites in Green Rice.

Pigmented rice grains are important resources for health and nutritional perspectives. Thus, a thorough dissection of the variation of nutrients and bioactive metabolites in different colored rice is of global interest. This study applied LC-MS-based widely targeted metabolite profiling and unraveled the variability of metabolites and nutraceuticals in long grain/non-glutinous black (BR), red (RR), green (GR), and white rice (WR) grains.

Strategy of stretched Coils: Insights from a single center experience.

Objective: A stretched coil, characterized by excessive elongation within the parent artery during a coil embolization procedure, poses a significant risk of forming a thrombus. This study reports on cases of stretched coils spanning 16 years and discusses effective assessment methods and treatment strategies.

Method: Retrospective analysis of the institutional database comprising 14 cases where stretched coils were observed during coil embolization procedures was conducted, starting from January 2007.

Phase Stability Improvement of a γ-CsPbI Perovskite Solar Cell Utilizing a Barium Bis(trifluoromethanesulfonimide) Solution.

The cesium lead iodide (CsPbI) perovskite solar cell possesses a wide band gap ranging from 1.65 to 1.75 eV, which is suitable for integration into a tandem structure along with a low-band-gap silicon solar cell.

A safe power controlling method for a phase-shift migration inverter to drive a high-power ultrasonic transducer.

The aim of this work is to investigate and analyze the operation mechanism and power control principle of a bolted Langevin type (BLT)-loaded phase-shifted control inverter and to find a safe power control method for a phase-shifted control inverter used to drive a high-power BLT by preventing the differential current (shock current) from occurring in the right branches of a phase-shifted full-bridge circuit. In this paper, by allowing the inverter operating frequency to operate under inductive loads that coincide with the zero points of voltage and current rather than the resonant frequency of the BLT, which results in the generation of a shock current in the right branch of the full-bridge circuit, the switches of the right-branch also enabled zero-voltage, zero-current switching on (ZVZCS turn-on). The proposed method can fundamentally eliminate the generation of shock current by realizing ZVZCS turn-on on the right-branch switch elements of the inverter.

Modifying antibody-FcRn interactions to increase the transport of antibodies through the blood-brain barrier.

The blood-brain barrier (BBB) largely excludes antibodies from entering the central nervous system, thus limiting the potential of therapeutic antibodies to treat conditions such as neurodegenerative diseases and neuro-psychiatric disorders. Here, we demonstrate that the transport of human antibodies across the BBB in mice can be enhanced by modulating their interactions with the neonatal Fc receptor (FcRn). When M252Y/S254T/T246E substitutions are introduced on the antibody Fc domain, immunohistochemical assays reveal widespread distribution of the engineered antibodies throughout the mouse brain.

Eight-and-a-half syndrome as the first presentation of multiple sclerosis in an Asian male: a case report.

Background: Multiple sclerosis is a diffuse chronic demyelinating disease of the central nervous system. It is relatively uncommon in the Asian population and even more so in males. Despite the usual involvement of the brainstem, eight-and-a-half syndrome remains a rare first presentation in multiple sclerosis.

Color balanced transparent luminescent solar concentrator based on a polydimethylsiloxane polymer waveguide with coexisting polar and non-polar fluorescent dyes.

Color balance is a critical concept in the application of functional transparent polymers from a customer's standpoint. In this study, multiple polar and non-polar fluorescent dyes are embedded simultaneously for the first time in a polydimethylsiloxane (PDMS) polymer matrix. Five dyes successfully coexist with the optimum blending ratio.

Falling into an identity crisis: Integrating identity into the assessment and management of falls in older adults.

Objectives: This article examines the psychological effects of falls for older adults through the lens of identity and suggests these may be integrated in the assessment and management of older patients within acute care and rehabilitation settings post-fall. An illustrative vignette is described to demonstrate this approach.

Conclusion: Falls in older adults are complex phenomena which can lead to an identity threat, sometimes manifest as psychological symptoms and poor engagement in post-fall rehabilitation.

A new variant position of head-up CPR may be associated with improvement in the measurements of cranial near-infrared spectroscopy suggestive of an increase in cerebral blood flow in non-traumatic out-of-hospital cardiac arrest patients: A prospective interventional pilot study.

Aim Of The Study: This study aimed to investigate the effect of the head-up position implemented during cardiopulmonary resuscitation (CPR) on cerebral blood flow (CBF) using near-infrared spectroscopy in out-of-hospital cardiac arrest patients.

Methods: Baseline characteristics (age, sex, cerebral performance category before cardiac arrest, witnessed cardiac arrest, bystander CPR, first monitored rhythm, no-flow time, prehospital low-flow time, CPR duration in the emergency department (ED), and reason for stopping CPR in the ED) were recorded. The changes of CBF were derived from the optical oscillation waveform measured by near-infrared spectroscopy in adult patients with out-of-hospital cardiac arrest by alternating head-up and supine positions at 4-minute intervals while performing CPR.

Genetic Diversity of Shanlan Upland Rice ( L.) and Association Analysis of SSR Markers Linked to Agronomic Traits.

Shanlan upland rice, a kind of unique rice germplasm in Hainan Island, was used to evaluate genetic diversity and association between SSR markers and agronomic traits. A total of 239 alleles were detected in 57 Hainan upland rice varieties using 35 SSR markers, and the number of alleles per locus was 2-19. The observed heterozygosity was 0.

Biomechanical forces enhance directed migration and activation of bone marrow-derived dendritic cells.

Mechanical forces are pervasive in the inflammatory site where dendritic cells (DCs) are activated to migrate into draining lymph nodes. For example, fluid shear stress modulates the movement patterns of DCs, including directness and forward migration indices (FMIs), without chemokine effects. However, little is known about the effects of biomechanical forces on the activation of DCs.

Leaf-inspired homeostatic cellulose biosensors.

An incompatibility between skin homeostasis and existing biosensor interfaces inhibits long-term electrophysiological signal measurement. Inspired by the leaf homeostasis system, we developed the first homeostatic cellulose biosensor with functions of protection, sensation, self-regulation, and biosafety. Moreover, we find that a mesoporous cellulose membrane transforms into homeostatic material with properties that include high ion conductivity, excellent flexibility and stability, appropriate adhesion force, and self-healing effects when swollen in a saline solution.

Self-Aggregation-Controlled Rapid Chemical Bath Deposition of SnO Layers and Stable Dark Depolarization Process for Highly Efficient Planar Perovskite Solar Cells.

Planar perovskite solar cells (PSCs) incorporating n-type SnO have attracted significant interest because of their excellent photovoltaic performance. However, the film fabrication of SnO is limited by self-aggregation and inhomogeneous growth of the intermediate phase, which produces poor morphology and properties. In this study, a self-controlled SnO layer is fabricated directly on a fluorine-doped tin oxide (FTO) surface through simple and rapid chemical bath deposition.

Changes in the Photoluminescence of Monolayer and Bilayer Molybdenum Disulfide during Laser Irradiation.

Various postsynthesis processes for transition metal dichalcogenides have been attempted to control the layer number and defect concentration, on which electrical and optical properties strongly depend. In this work, we monitored changes in the photoluminescence (PL) of molybdenum disulfide (MoS) until laser irradiation generated defects on the sample flake and completely etched it away. Higher laser power was required to etch bilayer MoS compared to monolayer MoS.

The relationship between acrosome reaction and polyunsaturated fatty acid composition in boar sperm.

This study investigated the relationship between acrosome reactions and fatty acid composition with respect to fertility in boar sperm. The acrosome reaction was induced more than 85% by 60 mM methyl-beta-cyclodextrin (MBCD), and plasma membrane integrity was significantly reduced dependent on the MBCD level in boar sperm (p < .05).

Inaccuracies in survey reporting of alcohol consumption.

Background: Alcohol consumption estimates in public health predominantly rely on self-reported survey data which is likely to underestimate consumption volume. Surveys tend to ask specifically about standard drinks and provide a definition or guide in an effort to gather accurate estimates. This study aimed to investigate whether the inclusion of the term standard drinks with pictorial guide is associated with an adjustment in self-reported alcohol volume.

Cellular organization of three germ layer cells on different types of noncovalent functionalized graphene substrates.

Graphene and its derivatives have seen a rapid rise in interest as promising biomaterials especially in the field of tissue engineering, regenerative medicine, and cell biology of late. Despite its proven potential in numerous biological applications, information regarding the relationship between the different forms of graphene and cell lineages is still lacking partly due to its topical emergence in cellular studies. Herein, we explore the biocompatibility of four types of graphene substrates (chemical vapor deposition grown graphene, mechanically exfoliated graphene, chemically exfoliated graphene oxide, and reduced graphene oxide) with three types of somatic cells (keratinocytes, hepatocytes, endothelial cells) derived from the three germ layers in relation to cell adhesion, proliferation, morphology, and gene expression.

Abnormal elastic modulus behavior in a crystalline-amorphous core-shell nanowire system.

We investigated the elastic modulus behavior of crystalline InAs/amorphous Al2O3 core-shell heterostructured nanowires with shell thicknesses varying between 10 and 90 nm by conducting in situ tensile tests inside a transmission electron microscope (TEM). Counterintuitively, the elastic modulus behaviors of InAs/Al2O3 core-shell nanowires differ greatly from those of bulk-scale composite materials, free from size effects. According to our results, the elastic modulus of InAs/Al2O3 core-shell nanowires increases, peaking at a shell thickness of 40 nm, and then decreases in the range of 50-90 nm.

Highly stretchable, mechanically stable, and weavable reduced graphene oxide yarn with high NO sensitivity for wearable gas sensors.

Stretchable gas sensors are important components of wearable electronic devices used for human safety and healthcare applications. However, the current low stretchability and poor stability of the materials limit their use. Here, we report a highly stretchable, stable, and sensitive NO gas sensor composed of reduced graphene oxide (RGO) sheets and highly elastic commercial yarns.

Highly conductive and environmentally stable gold/graphene yarns for flexible and wearable electronics.

Here, we fabricated high-performance gold/graphene yarns through a facile method by the electroless deposition of gold nanoparticles onto the surface of graphene yarns. The gold/graphene yarns are fabricated using a completely solution-based process that can be scaled up for practical applications. They possess high electrical conductivity (2.

A PbICl seed layer for obtaining efficient planar-heterojunction perovskite solar cells via an interdiffusion process.

Despite the previous reports on the fabrication of CHNHPbICl films via sequential deposition, the positioning and formation of PbI in MAPbICl perovskite films made from the seed layer containing PbI and PbCl in different ratios have not yet been addressed. In this study, the PbI content in a perovskite absorber layer is controlled by changing the PbCl ratio in a PbICl seed layer. The addition of PbCl in the seed layer facilitates PbI generation and affects the morphology of the perovskite film.

Public Awareness of Stroke and Its Predicting Factors in Korea: a National Public Telephone Survey, 2012 and 2014.

The aim of this study was to investigate time trends in the public awareness of stroke and its predicting factors. The target population was 9,600 community-dwelling adults, aged 19-79 years, in 16 metropolitan cities and provinces in Korea. The survey samples in 2012 and 2014 were selected separately (entirely different sets of subjects) using a proportionate quota sampling method.

Targeting Attenuated Interferon-α to Myeloma Cells with a CD38 Antibody Induces Potent Tumor Regression with Reduced Off-Target Activity.

Interferon-α (IFNα) has been prescribed to effectively treat multiple myeloma (MM) and other malignancies for decades. Its use has waned in recent years, however, due to significant toxicity and a narrow therapeutic index (TI). We sought to improve IFNα's TI by, first, attaching it to an anti-CD38 antibody, thereby directly targeting it to MM cells, and, second, by introducing an attenuating mutation into the IFNα portion of the fusion protein rendering it relatively inactive on normal, CD38 negative cells.

Molecular Description of Macroorchis spinulosus (Digenea: Nanophyetidae) Based on ITS1 Sequences.

We performed a molecular genetic study on the sequences of 18S ribosomal RNA (ITS1 region) gene in 4-day-old adult worms of Macroorchis spinulosus recovered in mice experimentally infected with metacercariae from crayfish in Jeollanam-do Province, Korea. The metacercariae were round, 180 μm in average diameter, encysted with 2 layers of thick walls, but the stylet on the oral sucker was not clearly seen. The adult flukes were oval shape, and 760-820 μm long and 320-450 μm wide, with anterolateral location of 2 large testes.

Ultrasensitive and highly selective graphene-based single yarn for use in wearable gas sensor.

Electric components based on fibers or textiles have been investigated owing to their potential applications in wearable devices. High performance on response to gas, drape-ability and washing durability are of important for gas sensors based on fiber substrates. In this report, we demonstrate the bendable and washable electronic textile (e-textile) gas sensors composed of reduced graphene oxides (RGOs) using commercially available yarn and molecular glue through an electrostatic self-assembly.