Publications by authors named "Yong Tong"

This systematic review with meta-analysis explores the global demographic and etiological variations of retinal vasculitis (RV), focusing on differences in frequency, age, sex, and etiology across diverse geographic populations. RV is an inflammatory condition that can lead to visual impairment, making understanding its variations essential for targeted screening and management. Systematic searches were conducted in multiple databases up to February, 2023, following PRISMA guidelines.

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Background: A high aspartate aminotransferase/platelet ratio index (APRI) predicts mortality in patients with severe infection. This study aims to assess the potential of APRI as a predictor for mortality in patients with HIV-associated (HTM).

Methods: Associations between APRI and CD4 count, white blood cell count, C-reactive protein (CRP) level, procalcitonin (PCT) level, and cytokines were assessed in 119 patients.

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Carbon-based anode materials have become a research hotspot for alkali metal ion batteries. Crucially, the electrochemical performance of carbon materials must be improved by appropriate means such as micro-nano structure design and atomic doping. Herein, antimony doped hard carbon materials are prepared by anchoring Sb atoms on nitrogen-doped carbon (SbNC).

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Bismuth (Bi)-based materials have attracted great attention as anodes in potassium ion batteries (PIBs) for their high theoretical capacity and suitable voltage range. Herein, the authors report a unique spindle-like structured Bi@N-doped carbon composite (SPB@NC) consisting of interconnected nano-Bi coated heteroatom-doped hard carbon layer via an interesting in situ carbon thermal reduction method. The special interconnected Bi nanoparticles gradually form porous structure with ample inner voids for accommodating volume variations while the N-doped carbon layer not only keeps the electrode stable, but also contributes to rapid electron/ion transfer.

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Due to their characteristics of high capacity and appropriate potassiation/depotassiation potential, Sb-based materials have become a class of promising anode materials for potassium ion batteries (PIBs). However, the huge strain induced by potassiation/depotassiation limits their ability to periodically accept/release K . Herein, a composite with FeSb nanoparticles embedded in a 3D porous carbon framework (FeSb @3DPC) is successfully constructed as an extremely stable anode material for PIBs.

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Antimony (Sb) has attracted considerable attention as an anode material for potassium ion batteries (PIBs) because of its high theoretical capacity. Nevertheless, owing to the large radius of K, apparent volume expansion occurs during the reaction between Sb and K, which will undermine the stability of the electrode. Accordingly, a dual-carbon confinement strategy is regarded as an effective method for handling this issue.

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The advancement of potassium ion batteries (PIBs) stimulated by the dearth of lithium resources is accelerating. Major progresses on the electrochemical properties are based on the optimization of electrode materials, electrolytes, and other components. More significantly, the prerequisites for optimizing these key compositions are in-depth and comprehensive exploration of electrochemical reaction processes, including the evolution of morphology and structure, phase transition, interface behaviors, and K movement, etc.

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It is of great significance to develop a new kind of green and environmentally friendly potassium ion energy storage device, with stable structures and large specific capacity. In this manuscript, a facile and robust way is reported to construct nitrogen doped porous carbon flake (NPCF) through NaCl template and pyrolysis method. 3D porous structures can be formed and interconnected NPCF are used as potassium ion batteries (PIBs) anode.

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Potassium-ion batteries (PIBs) have attracted widespread attention in recent years due to their potential advantages such as low cost and high energy density. However, the large radius of K and the low potassium storage capacity of some electrode materials limit their development. Antimony (Sb)-based materials are considered to be promising anode materials for PIBs in view of their high K storage capacity and low potassiation potential.

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Squalene is widely used in pharmaceutical, nutraceutical, cosmetics and other fields because of its strong antioxidative, antibacterial and anti-tumor activities. In order to produce squalene, a gene ispA encoding farnesyl pyrophosphate synthase was overexpressed in a previously engineered Escherichia coli strain capable of efficiently producing terpenoids, resulting in a chassis strain that efficiently synthesizes triterpenoids. Through phylogenetic analysis, screening, cloning and expression of squalene synthase derived from different prokaryotes, engineered E.

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In view of rich potassium resources and their working potential, potassium-ion batteries (PIBs) are deemed as next generation rechargeable batteries. Owing to carbon materials with the preponderance of durability and economic price, they are widely employed in PIBs anode materials. Currently, porosity design and heteroatom doping as efficacious improvement strategies have been applied to the structural design of carbon materials to improve their electrochemical performances.

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Article Synopsis
  • Voriconazole (VRC), an antifungal, shows significant variability in effectiveness and toxicity among individuals, affected by inflammatory markers like C-reactive protein (CRP).
  • The study investigates how capsular polysaccharide A (PSA), derived from probiotics, can improve voriconazole metabolism by reducing inflammation induced by lipopolysaccharide (LPS) in germ-free animals.
  • PSA not only normalized voriconazole levels by impacting inflammatory cytokines and metabolic pathways but also presents a potential adjunct therapy for better managing voriconazole treatment in patients.
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Hemophagocytic lymphohistiocytosis (HLH) is a high-fatality disease caused by hereditary or acquired immune dysfunction, and is characterized by pathological inflammatory response. Primary HLH (pHLH) has hereditary genetic defects, and secondary HLH (sHLH) is caused by a variety of underlying diseases. Here, we report the case of a patient with aggressive natural killer cell leukemia and HLH-related gene defects who achieved long-term survival after treatment.

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Chronic hepatitis B virus (CHB) infection is one of the primary risk factors associated with the development of hepatocellular carcinoma (HCC). Despite having been extensively studied, diagnosing early-stage HCC remains challenging, and diagnosed patients have a poor (3-5%) survival rate. Identifying new approaches to detect changes in the serum metabolic profiles of patients with CHB and liver cirrhosis (LC) may provide a valuable approach to better detect HCC at an early stage when it is still amenable to treatment, thereby improving patient prognosis and survival.

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Designing electrode structures with high activity is very significant for energy conversion systems. However, single electrode materials often exhibit poor electronic transportation. To address this issue, we prepared P-FeO nanowire arrays through a convenient hydrothermal and phosphation method.

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Background: The aim of this study was to investigate the association between telomerase reverse transcriptase () gene polymorphisms and acute myeloid leukemia (AML) susceptibility in a Chinese Han population.

Methods: A total of 102 AML patients and 108 healthy controls were enrolled in this case-control study. gene rs2853669 and rs2736100 polymorphisms were genotyped via polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).

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The pathogenesis and etiology of schizophrenia (SCZ) remains unclear. Accumulating studies showed that complex interrelationships between brain-derived neurotrophic factor (BDNF) and an imbalanced redox system has a crucial role in the psychopathology of SCZ. However, the influence of the interrelationships of BDNF and superoxide dismutase (SOD) on cognitive impairment and clinical symptomatology in drug-naive first-episode (DNFE) SCZ patients has not been studied thoroughly.

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We present a Recurrent Neural Network (RNN) Encoder-Decoder model to generate Chinese pop music lyrics to hide secret information. In particular, on a given initial line of a lyric, we use the LSTM model to generate the next Chinese character or word to form a new line. In so doing, we generate the entire lyric from what has been generated so far.

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Both obesity and arsenic exposure are global public health problems that are associated with increased risk of renal disease. The effect of whole-life exposure to environmentally relevant levels of arsenic within dietary high fat diet on renal pathogenesis were examined. In this study, C57BL/6 J mice were parentally exposed to 100 ppb arsenic before conception.

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BACKGROUND The objective of this study was to detect the association between ERCC excision repair 2, TFIIH core complex helicase subunit (ERCC2) gene polymorphisms and diffuse large B-cell lymphoma (DLBCL) susceptibility. MATERIAL AND METHODS This study used a case-control design. ERCC2 gene rs1799793 (Asp312Asn) and rs13181 (Lys751Gln) polymorphisms were genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) both in DLBCL patients and healthy controls.

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Understanding the loss of conserved genes is critical for determining how phenotypic diversity is generated. Here we focus on the evolution of DCC, a gene that encodes a highly conserved neural guidance receptor. Disruption of DCC in animal models and humans results in major neurodevelopmental defects including commissural axon defects.

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Homeobox genes play crucial roles for the development of multicellular eukaryotes. We have generated a revised list of all homeobox genes for Caenorhabditis elegans and provide a nomenclature for the previously unnamed ones. We show that, out of 103 homeobox genes, 70 are co-orthologous to human homeobox genes.

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Unravelling how neurons are guided during vertebrate embryonic development has wide implications for understanding the assembly of the nervous system. During embryogenesis, migration of neuronal cell bodies and axons occurs simultaneously, but to what degree they influence each other's development remains obscure. We show here that within the mouse embryonic spinal cord, commissural axons bisect, delimit or preconfigure ventral interneuron cell body position.

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