Effect of Qigong exercise on quality of life and cortisol in patients with cancer: a non-randomized controlled trial.

Purpose: The aim of this study was to investigate the effect of a 6-month Guolin Qigong on quality of life and serum cortisol among patients with cancer.

Methods: This study was a two-arm and non-randomized controlled trial. Forty-nine patients with cancer who were over 18 years of age and diagnosed with cancer were enrolled in this study and assigned to either the Guolin Qigong intervention group (IG, n = 26) or the usual care group (UC, n = 23) for 6 months.

Pharmacological Effects of a Ginseng-Containing Chinese Medicine Formula in Treating Hepatocellular Carcinoma Based on Comprehensive Bioinformatics and Experimental Validation.

Ginseng-containing Shentao Ruangan granules (STR) have been a well-known Chinese medicine prescription for the treatment of hepatocellular carcinoma (HCC) in China for decades. This study aimed to establish an experimental framework to decipher the underlying mechanism of STR in the treatment of HCC. Microarray analysis, network pharmacology, RNA-sequencing (RNA-seq), bioinformatics analysis, and and experiments were used as integrated approaches to uncover the effects and mechanisms of action of STR.

A 17.73 % Solar-To-Hydrogen Efficiency with Durably Active Catalyst in Stable Photovoltaic-Electrolysis Seawater System.

Developing durably active catalysts to tackle harsh voltage polarization and seawater corrosion is pivotal for efficient solar-to-hydrogen (STH) conversion, yet remains a challenge. We report a durably active catalyst of NiCr-layered double hydroxide (RuNiCr-LDH) with highly exposed Ni-O-Ru units, in which low-loading Ru (0.32 wt %) is locked precisely at defect lattice site (Ru) by Ni and Cr.

The complete chloroplast genome and phylogenetic analysis of a rare species (Schisandraceae).

Lin & Shui, 2011, belongs to the family Schisandraceae and was recently added to the List of National Key Protected Wild Plants in China. We report the complete chloroplast (cp) genome of using Illumina Nova-Seq 6000 platform. The results showed that the cp genome size of was 144,288 bp, which contained a small single-copy (SSC) region (17,862 bp), a large single-copy (LSC) region (93,332 bp), and a pair of inverted repeat (IR) regions (16,547 bp).

USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer.

The ubiquitin-specific protease (USP) family is the largest and most diverse deubiquitinase (DUBs) family and plays a significant role in maintaining cell homeostasis. Dysregulation of USPs has been associated with carcinogenesis of various tumors. We identified that USP19 was downregulated in pancreatic tumor tissues and forced expression of USP19 diminished tumorigenicity of pancreatic cancer.

Discovery of a Novel Public Antibody Lineage Correlated With Inactivated SARS-CoV-2 Vaccine and the Resultant Neutralization Activity.

While the SARS-CoV-2 vaccine offers 70%-95% protection effectiveness against Coronavirus disease 2019 (COVID-19), a portion of recipients do not produce adequate protective immune responses, particularly, neutralizing antibodies (nAbs). Previous studies of COVID-19 patients have identified several public antibody lineages, such as IGHV3-30, IGHV3-33, IGHV3-53, IGHV1-58, and IGHV1-24. However, it remains unclear how these public antibodies evolve during vaccination or whether there are any special antibody lineages correlated with SARS-CoV-2 vaccination.

Single-layer MoS/graphene-based stable on-chip Zn-ion microbattery for monolithically integrated electronics.

Self-powered microelectronics are essential for the sustained and autonomous operations of wireless electronics and microrobots. However, they are challenged by integratable microenergy supplies. Herein, we report a single-layer (SL) MoS/graphene heterostructure for stable Zn-ion microbatteries.

The complete chloroplast genome sequence of (Magnoliaceae).

is an evergreen garden plant with attractive and fragrant flowers. exhibits both interspecific and intraspecific phenotypic variability. However, the genetic diversity of has not been thoroughly investigated.

Direct Evidence of Breakdown of Spin Statistics in Ion-Atom Charge Exchange Collisions.

Recent experimental studies have questioned the validity of spin statistics assumptions, particularly in charge exchange processes occurring in atomic MeV collisions. Here, we study spin-resolved single electron capture processes in collisions between C^{3+} ions and helium within an energy range of 1.25-400  keV/u.

Hepatocyte-specific SLC27A4 deletion ameliorates nonalcoholic fatty liver disease in mice via suppression of phosphatidylcholine-mediated PXR activation.

Background: The protein Solute carrier family 27 member 4 (SLC27A4) is crucial for fatty acid synthesis and β-oxidation, but its role in hepatic steatosis and nonalcoholic fatty liver disease (NAFLD) progression is not fully understood.

Methods: Mice with AAV-mediated overexpression of Slc27a4 in liver and hepatocytes-specific deletion of Slc27a4 were fed a standard chow diet, a high-fat diet (HFD), or a methionine and choline-deficient diet (MCD). Serum and liver tissues were collected and analyzed by biochemical assay, histology, lipidomic analysis, RNA-seq analysis, qPCR, western blot and immunofluorescence.

High-Performance Intermetallic PtCo/C Electrocatalyst for the Oxygen Reduction Reaction Synthesized by Pre-Lithiation Method.

Fuel cells are recognized as promising alternatives to existing conventional energy systems for a sustainable future. However, the synthesis of efficient and robust platinum (Pt) based catalysts remains a challenge for practical fuel cell applications. Herein, the PtCo/C nanoparticles with about 4.

Relationship between root system-soil C:N:P and soil microbial diversity at different evolutionary stages of scrub in arid desert grassland, Northern China.

Scrub root systems play a crucial role in preventing soil erosion and nutrient loss. However, the effects of the root system configuration on soil nutrient dynamics and microbial changes at various evolutionary stages remain poorly understood. In this study, we investigated the relationship between soil physical and chemical properties and the diversity of bacteria and fungi throughout the evolutionary stages of the scrub root systems.

Uremic syndrome with newly diagnosed HIV infection: reflections on a particular case.

Introduction: Diagnosis with Western blot test (WB) may not provide clear results for certain patients, including those who are not infected with human immunodeficiency virus (HIV) but produce non-specific reactions, individuals in the HIV window period (WP), those with acute HIV infection, and advanced acquired immunodeficiency syndrome (AIDS) patients. HIV-positive individuals face an elevated risk of developing kidney disease. HIV peritoneal dialysis patients may be more susceptible to catheter-related infections.

Chemical characteristics of sand barriers are accelerated degradation by ultraviolet irradiation and water.

The implementation of sand barriers measures constitutes a crucial element in desertification control, providing a solid theoretical foundation for the future application and pretreatment of sand barriers in production practices. To address the specific damage types predominant in desert environments, we executed simulations of ultraviolet irradiation and rainfall phenomena on mechanical sand barriers in sandy areas and also inspected the variations in chemical properties during accelerated aging processes. The findings unequivocally demonstrate that: (1) The synergistic impact of ultraviolet irradiation and water accelerated the deformation and fracturing of the sand barriers, thereby causing a partial degradation of its chemical properties and conspicuous lignin oxidation; (2) The fissure of the sand barrier deepened, resulting in structural alterations.

Recent advances in hydrogel-based flexible strain sensors for harsh environment applications.

Flexible strain sensors are broadly investigated in electronic skins and human-machine interaction due to their light weight, high sensitivity, and wide sensing range. Hydrogels with unique three-dimensional network structures are widely used in flexible strain sensors for their exceptional flexibility and adaptability to mechanical deformation. However, hydrogels often suffer from damage, hardening, and collapse under harsh conditions, such as extreme temperatures and humidity levels, which lead to sensor performance degradation or even failure.

Prediction of testicular histology in azoospermia patients through deep learning-enabled two-dimensional grayscale ultrasound.

Testicular histology based on testicular biopsy is an important factor for determining appropriate testicular sperm extraction surgery and predicting sperm retrieval outcomes in patients with azoospermia. Therefore, we developed a deep learning (DL) model to establish the associations between testicular grayscale ultrasound images and testicular histology. We retrospectively included two-dimensional testicular grayscale ultrasound from patients with azoospermia (353 men with 4357 images between July 2017 and December 2021 in The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) to develop a DL model.

UV irradiation behavior of sand barriers in the process of desertification control.

sand barriers degrade under sunlight exposure, resulting in diminished protective performance and shortened service life in desertification control. To address the unresolved issue of photoinduced damage and degradation in sand barriers, we conducted simulations to assess the accelerated damage effect of ultraviolet (UV) rays during solar exposure of sand barriers. Our analysis focused on elucidating the mechanism of UV irradiation in sand barriers by examining the structural and material property changes that occur during the degradation process.

Ultrasound viscoelastic imaging in the noninvasive quantitative assessment of chronic kidney disease.

Background: This study aims to evaluate the clinical application value of ultrasound viscoelastic imaging in noninvasive quantitative assessment of chronic kidney disease (CKD).

Methods: A total of 332 patients with CKD and 190 healthy adults as a control group were prospectively enrolled. Before kidney biopsy, ultrasound viscoelastic imaging was performed to measure the mean stiffness value (Emean), mean viscosity coefficient (Vmean), and mean dispersion coefficient (Dmean) of the renal.

Prediction of high-risk prostate cancer based on the habitat features of biparametric magnetic resonance and the omics features of contrast-enhanced ultrasound.

Rationale And Objectives: To predict high-risk prostate cancer (PCa) by combining the habitat features of biparametric magnetic resonance imaging (bp-MRI) with the omics features of contrast-enhanced ultrasound (CEUS).

Materials And Methods: This study retrospectively collected patients with PCa confirmed by histopathology from January 2020 to June 2023. All patients underwent bp-MRI and CEUS of the prostate, followed by a targeted and transrectal systematic prostate biopsy.

Advancing Heterogeneous Organic Synthesis With Coordination Chemistry-Empowered Single-Atom Catalysts.

For traditional metal complexes, intricate chemistry is required to acquire appropriate ligands for controlling the electron and steric hindrance of metal active centers. Comparatively, the preparation of single-atom catalysts is much easier with more straightforward and effective accesses for the arrangement and control of metal active centers. The presence of coordination atoms or neighboring functional atoms on the supports' surface ensures the stability of metal single-atoms and their interactions with individual metal atoms substantially regulate the performance of metal active centers.

A novel homozygous mutation in the DNAAF3 gene leads to severe asthenozoospermia and teratospermia.

Primary ciliary dyskinesia (PCD) is an autosomal recessive genetic disorder characterized by ultrastructural defects in the cilia or flagella of cells, causing respiratory abnormalities, sinusitis, visceral transposition, and male infertility. DNAAF3 plays an important role in the assembly and transportation of axonemal dynein complexes in cilia or flagella and has been shown to be associated with PCD. To date, only two cases of PCD with infertility associated with DNAAF3 mutations have been reported, and no mouse models for this gene have been successfully constructed.