Comparative metabolomic analysis of Haematococcus pluvialis during hyperaccumulation of astaxanthin under the high salinity and nitrogen deficiency conditions.

Revealing the differences of metabolite profiles of H. pluvialis during hyperaccumulation of astaxanthin under the high salinity and nitrogen deficiency conditions was the key issues of the present study. To investigate the optimum NaCl and NaNO concentration and the corresponding metabolic characteristic related to the astaxanthin accumulation in H.

Notoginsenoside R1 improves intestinal microvascular functioning in sepsis by targeting Drp1-mediated mitochondrial quality imbalance.

Context: Sepsis can result in critical organ failure, and notoginsenoside R1 (NGR1) offers mitochondrial protection.

Objective: To determine whether NGR1 improves organ function and prognosis after sepsis by protecting mitochondrial quality.

Materials And Methods: A sepsis model was established in C57BL/6 mice using cecum ligation puncture (CLP) and an model with lipopolysaccharide (LPS, 10 µg/mL)-stimulated primary intestinal microvascular endothelial cells (IMVECs) and then determine NGR1's safe dosage.

Effects of Anesthetics on Cardiac Repolarization in Adults: A Network Meta-Analysis of Randomized Clinical Trials.

Objectives: Prolongation of cardiac repolarization, especially the heart rate-corrected QT (QTc) interval, is associated with life-threatening dysrhythmias. This study aimed to identify the anesthetic with the lowest risk of prolonging cardiac repolarization and provide guidance for anesthesia management in patients with cardiac diseases or long QT syndrome.

Methods: Randomized controlled trials (RCTs) comparing the effects of anesthetics on cardiac repolarization indices were searched for in multiple databases.

Validation of a Wearable System for Lower Extremity Assessment.

Objective: Remote assessment and diagnosis of functional impairment caused by osteoarthritis (OA) of the knee can achieve early intervention of patients' functional impairment, prevent the deterioration of OA of the knee, and provide functional remote screening for patients with knee OA. This study introduced an inertial measurement unit (IMU) sensor-based system to assess lower extremity function and perform gait analysis. Then, we compared its accuracy to gold-standard motion capture and gait measurement systems.

Predisposing factors for allogeneic blood transfusion in patients with ankylosing spondylitis undergoing primary unilateral total hip arthroplasty: a retrospective study.

Background: The transfusion rate is relatively high in patients with ankylosing spondylitis (AS) undergoing total hip arthroplasty (THA). However, relevant studies focusing on the predisposing factors for transfusion with a large sample size are lacking. This study aimed to investigate the incidence of and risk factors for allogeneic blood transfusion in patients with AS undergoing primary unilateral THA.

Identification and whole-genome sequencing analysis of Vibrio vulnificus strains causing pearl gentian grouper disease in China.

Vibrio vulnificus is a pathogenic bacterium that causes disease in marine fish, affecting fish farming and human health worldwide. In May 2021, in the Bohai Bay region, a disease broke out in commercially farmed pearl gentian grouper (♀Epinephelus fuscoguttatus × ♂Epinephelus lanceolatus), causing huge economic losses. The diseased fish had skin lesions, water accumulation in their abdomens, and showed tissue and organ damage.

Isolate sets partition benefits community detection of parallel Louvain method.

Community detection is a vital task in many fields, such as social networks, and financial analysis, to name a few. The Louvain method, the main workhorse of community detection, is a popular heuristic method based on modularity. But it is difficult for the sequential Louvain method to deal with large-scale graphs.

A siamese network with adaptive gated feature fusion for individual knee OA features grades prediction.

Grading individual knee osteoarthritis (OA) features is a fine-grained knee OA severity assessment. Existing methods ignore following problems: (1) more accurately located knee joints benefit subsequent grades prediction; (2) they do not consider knee joints' symmetry and semantic information, which help to improve grades prediction performance. To this end, we propose a SE-ResNext50-32x4d-based Siamese network with adaptive gated feature fusion method to simultaneously assess eight tasks.

Cyanide-Bridged Polynuclear and One-Dimensional FeIII-MnIII/II Bimetallic Complexes Based-on Pentacyanoferrite(III) Building Block: Synthesis, Crystal Structures, and Magnetic Properties.

In this contribution, based-on the structurally confirmed pentacyanometallate (PPh4)2[Fe(CN)5(imidazole)]·(imidazole)·H2O (1) and the manganese compounds [Mn(L)(H2O)2]ClO4 (L = N,N-ethylenebis(3-methoxysalicylideneiminate) or [Mn(MAC)(H2O)Cl]ClO4 (MAC = 2,13-dimethyl-3,6,9,12,18-pentaazabicyclo-[12.3.1]octadeca-1(18),2,12,14,16-pentaene), two new cyanide-bridged bimetallic FeIII-MnIII/II complexes [Mn(L)(H2O)]3[Fe(CN)5(imidazole)](ClO4) (2) and [Mn(MAC)][Fe(CN)5(imidazole)]·CH3OHn (3) were successfully synthesized and characterized by elemental analysis, IR spectroscopy and X-ray structure determination.

A Lanthanide-Containing Coordination Polymer Using Tetraphenylethene-Based Linkers with Selective Fe Sensing and Efficient Iodine Adsorption Activities.

As a star ligand, the construction of coordination polymers (CPs) based on tetrakis(4-carboxyphenyl)ethylene (H) has drawn much attention, due to not only the various coordination configurations but also the intriguing chromophore feature causing aggregation-induced emission (AIE). Herein, by the solvothermal reaction of H as connected nodes with lanthanide La(III) salts, the first example of the La(III)--based CP () has been obtained. The structural analyses indicate that exhibits a 3D framework connected by the sharing carboxylate groups with two kinds of 1D rhombic channels when viewed along the direction.

A rare octacoordinated mononuclear iron(III) spin-crossover compound: synthesis, crystal structure and magnetic properties.

The chemistry of transition-metal complexes with unusually high coordination numbers has been of interest because of their application in catalytic and biological systems. Deprotonation of the ionogenic tetradentate ligand 6,6'-bis(1H-tetrazol-5-yl)-2,2'-bipyridine [Hbipy(ttr)] in the presence of iron(III) and tetra-n-butylammonium bromide, [n-BuN]Br, in solution resulted in the synthesis of a rare octacoordinated anionic mononuclear complex, tetra-n-butylammonium bis[6,6'-bis(tetrazol-1-id-5-yl)-2,2'-bipyridine]iron(III) methanol hemisolvate dihydrate, (CHN)[Fe(CHN)]·0.5CHOH·2HO or [n-BuN][Fe{bipy(ttr)}]·0.

Self-assembly of a cobalt(II)-based metal-organic framework as an effective water-splitting heterogeneous catalyst for light-driven hydrogen production.

The solar photocatalysis of water splitting represents a significant branch of enzymatic simulation by efficient chemical conversion and the generation of hydrogen as green energy provides a feasible way for the replacement of fossil fuels to solve energy and environmental issues. We report herein the self-assembly of a Co-based metal-organic framework (MOF) constructed from 4,4',4'',4'''-(ethene-1,1,2,2-tetrayl)tetrabenzoic acid [or tetrakis(4-carboxyphenyl)ethylene, HTCPE] and 4,4'-bipyridyl (bpy) as four-point- and two-point-connected nodes, respectively. This material, namely, poly[(μ-4,4'-bipyridyl)[μ-4,4',4'',4'''-(ethene-1,1,2,2-tetrayl)tetrabenzoato]cobalt(II)], [Co(CHO)(CHN)], crystallized as dark-red block-shaped crystals with high crystallinity and was fully characterized by single-crystal X-ray diffraction, PXRD, IR, solid-state UV-Vis and cyclic voltammetry (CV) measurements.

Tuning of crystallization method and ligand conformation to give a mononuclear compound or two-dimensional SCO coordination polymer based on a new semi-rigid V-shaped bis-pyridyl bis-amide ligand.

With the new semi-rigid V-shaped bidentate pyridyl amide compound 5-methyl-N,N'-bis(pyridin-4-yl)benzene-1,3-dicarboxamide (L) as an auxiliary ligand and the Fe ion as the metal centre, one mononuclear complex, bis(methanol-κO)bis[5-methyl-N,N'-bis(pyridin-4-yl)benzene-1,3-dicarboxamide-κN]bis(thiocyanato-κN)iron(II), [Fe(SCN)(CHNO)(CHOH)] (1), and one two-dimensional coordination polymer, catena-poly[[[bis(thiocyanato-κN)iron(II)]-bis[μ-5-methyl-N,N'-bis(pyridin-4-yl)benzene-1,3-dicarboxamide-κN:N']] methanol disolvate dihydrate], {[Fe(SCN)(CHNO)]·2CHOH·2HO} (2), were prepared by slow evaporation and H-tube diffusion methods, respectively, indicating the effect of the method of crystallization on the structure type of the target product. Both complexes have been structurally characterized by elemental analysis, IR spectroscopy and single-crystal X-ray crystallography. The single-crystal X-ray diffraction analysis shows that L functions as a monodentate ligand in mononuclear 1, while it coordinates in a bidentate manner to two independent Fe(SCN) units in complex 2, with a different conformation from that in 1 and the ligands point in two almost orthogonal directions, therefore leading to a two-dimensional grid-like network.

Fabrication and characterization of PVA/CS-PCL/gel multi-scale electrospun scaffold: simulating extracellular matrix for enhanced cellular infiltration and proliferation.

A new bi-component poly(vinylalcohol)(PVA)/chitosan(CS)-poly(e-caprolactone)(PCL)/gelatin(Gel) multiscale electrospun scaffold was developed and analyzed in comparison with several other single scale systems. To mimic the native extracellular matrix in composition and structure and promote the migration of cells inside the scaffold, PVA/CS composite nanofibers (102 ± 52 nm) and PCL/Gelcomposite microfiber (2.5 ± 1.

A Versatile Porous Silver-Coordinated Material for the Heterogeneous Catalysis of Chemical Conversion with Propargylic Alcohols and CO.

The efficient transformation of carbon dioxide into useful chemical feedstock is of great significance, attracting intense research interest. The widely studied porous-coordinated polymers possess large pores to adsorb guest molecules and further allow the contact and to transfer the substrate molecule within their microenvironment. Here we present the synthesis of a silver-based metal-organic frameworks (MOFs) material with a three-dimensional structure by incorporating a tetraphenyl-ethylene moiety as the four-point connected node via the solvothermal method.

A thermal- and light-induced switchable one-dimensional rare loop-like spin crossover coordination polymer.

Rare loop-like isostructural one-dimensional coordination polymer (1D-CP) systems formulated as {Fe(DPIP)(NCSe)}·4DMF (1) and {Fe(DPIP)(NCSe)}·4DMF (2) were obtained by self-assembling Fe and pseudohalide NCX(X = S, Se) ions in presence of the V-shaped bidentate bridging ligand, namely, N,N'-dipyridin-4-ylisophthalamide (DPIP), and were characterized by elemental analysis, IR spectroscopy, TGA, single crystal X-ray diffraction and powder X-ray diffraction. The magnetic studies show that complex 2 undergoes a complete thermally induced spin crossover (SCO) behavior centered at T = 120 K with ca. 5 K thermal hysteresis loop and light-induced excited spin state trapping effect (LIESST) with T = 65 K.

A cyanide-bridged Fe-Mn heterobimetallic one-dimensional coordination polymer: synthesis, crystal structure, experimental and theoretical magnetism investigation.

A new cyanide-bridged Fe-Mn heterobimetallic coordination polymer (CP), namely catena-poly[[[N,N'-(1,2-phenylene)bis(pyridine-2-carboxamidato)-κN,N',N'',N''']iron(III)]-μ-cyanido-κC:N-[bis(4,4'-bipyridine-κN)bis(methanol-κO)manganese(II)]-μ-cyanido-κN:C], {[FeMn(CHNO)(CN)(CHN)(CHOH)]ClO}, (1), was prepared by the self-assembly of the trans-dicyanidoiron(III)-containing building block [Fe(bpb)(CN)] [bpb = N,N'-(1,2-phenylene)bis(pyridine-2-carboxamidate)], [Mn(ClO)]·6HO and 4,4'-bipyridine, and was structurally characterized by elemental analysis, IR spectroscopy, single-crystal X-ray crystallography and powder X-ray diffraction (PXRD). Single-crystal X-ray diffraction analysis shows that CP 1 possesses a cationic linear chain structure consisting of alternating cyanide-bridged Fe-Mn units, with free perchlorate as the charge-balancing anion, which can be further extended into a two-dimensional supramolecular sheet structure via inter-chain π-π interactions between the 4,4'-bipyridine ligands. Within the chain, each Mn ion is six-coordinated by an N unit and is involved in a slightly distorted octahedral coordination geometry.

Various Structural Types of Cyanide-Bridged Fe-Mn Bimetallic Coordination Polymers (CPs) and Polynuclear Clusters Based-on A New Tricyanoiron(III)Building Block: Synthesis, Crystal Structures, and Magnetic Properties.

Four cyanide-bridged Fe-Mn complexes {[Fe(qxcq)(CN)][Mn(L)(HO)]}[Mn(L)(HO)(CHOH)](ClO)·1.5MeOH·0.5HO (L = (3-methoxy-5-bromosalicylideneiminate) (2), {[Fe(qxcq)(CN)][Mn(L)]}·0.

A new three-dimensional cobalt(II) coordination polymer based on V-shaped 3,4'-oxydibenzoate: synthesis, crystal structure and magnetic properties.

A new coordination polymer (CP), namely poly[(μ-4,4'-bipyridine)(μ-3,4'-oxydibenzoato)cobalt(II)], [Co(CHO)(CHN)] or [Co(3,4'-obb)(4,4'-bipy)] (1), was prepared by the self-assembly of Co(NO)·6HO with the rarely used 3,4'-oxydibenzoic acid (3,4'-obbH) ligand and 4,4'-bipyridine (4,4'-bipy) under solvothermal conditions, and has been structurally characterized by elemental analysis, IR spectroscopy, single-crystal X-ray crystallography and powder X-ray diffraction (PXRD). Single-crystal X-ray diffraction reveals that each Co ion is six-coordinated by four O atoms from three 3,4'-obb ligands, of which two function as monodentate ligands and the other as a bidentate ligand, and by two N atoms from bridging 4,4'-bipy ligands, thereby forming a distorted octahedral CoNO coordination geometry. Adjacent crystallographically equivalent Co ions are bridged by the O atoms of 3,4'-obb ligands, affording an eight-membered CoOC ring which is further extended into a two-dimensional [Co(3,4'-obb)] sheet along the ab plane via 3,4'-obb functioning as a bidentate bridging ligand.

A Novel Memory-Scheduling Strategy for Large Convolutional Neural Network on Memory-Limited Devices.

Recently, machine learning, especially deep learning, has been a core algorithm to be widely used in many fields such as natural language processing, speech recognition, object recognition, and so on. At the same time, another trend is that more and more applications are moved to wearable and mobile devices. However, traditional deep learning methods such as convolutional neural network (CNN) and its variants consume a lot of memory resources.

An unprecedented hetero-bimetallic three-dimensional spin crossover coordination polymer based on the tetrahedral [Hg(SeCN)] building block.

Self-assembly of octahedral FeII ions, trans-1,2-bis(4-pyridyl)ethane (bpe) bridging ligands and [Hg(XCN)4]2- (X = S (1), Se (2)) tetrahedral building blocks has afforded a new type of hetero-bimetallic HgII-FeII spin-crossover (SCO) 3D 6,4-connected coordination polymer (CP) formulated {Fe(bpe)[Hg(XCN)4]}n. For X = S (1), the ligand field is close to the crossing point but 1 remains paramagnetic over all temperatures. In contrast, for X = Se (2) the complex undergoes complete thermal induced SCO behaviour centred at T1/2 = 107.