Publications by authors named "Yoneda A"

Purpose: To assess the impact of the relationship between renal pedicles and tumors on surgical outcomes in patients with non-high-risk abdominal neuroblastoma.

Methods: We retrospectively analyzed cases of neuroblastoma without metastasis treated at our hospital between March 2002 and December 2023. Cases in which surgical resection was performed were divided into three groups according to imaging findings at the time of diagnosis and before surgery: Group E (tumor encasing renal pedicles), Group C (tumor in contact with renal pedicles), and Group S (tumor separated from renal pedicles).

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Decades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heterologous hosts has remained a challenge. We discovered that a protein evolved from the machinery involved in building plant cell walls is the crucial link in the biosynthesis of SGAs.

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A new microporous supramolecular-framework Ru(II)-porphyrin catalyst containing non-covalent interactions between pyrenylphenyl moieties at the -position of the porphyrin ring is synthesised and structurally characterised. This recyclable catalyst expedites styrene epoxidation more efficiently than homogeneous Ru-porphyrin catalytic systems.

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Background: Pediatric pancreatic tumors are rare and account for < 0.1% of all childhood cancers. The primary treatment for pancreatic tumors is surgical resection.

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  • * It highlights the complexities of performing allogeneic transplants amid active infections, as they typically have poor outcomes.
  • * A specific case is presented about a 5-year-old boy with disseminated infection who received granulocyte transfusions from his mother and underwent successful haploidentical stem cell transplantation from his father after immunosuppressive treatment for SAA.
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Introduction: The systemic inflammatory score (SIS), a new inflammatory marker based on a combination of the lymphocyte-to-monocyte ratio (LMR) and serum albumin concentration, has been reported to be a useful prognostic marker for several malignancies. The authors conducted this retrospective study on data from a cohort of esophageal cancer patients undergoing potentially curative resection to clarify the value of SIS as a prognostic marker for clinical outcome in this population.

Methods: This retrospective cohort study included 32 patients who underwent thoracoscopic esophagectomy after neoadjuvant chemotherapy for esophageal cancer between January 2016 and December 2019.

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An upside-down stomach is a rare type of hiatal hernia. An 83-year-old woman presented to the emergency room with abdominal pain and vomiting. Computed tomography revealed an upside-down stomach and the incarceration of a part of the gastric body into the abdominal cavity.

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  • - The study examined why some patients with type 1 macular neovascularization (MNV) successfully switched to faricimab after being unresponsive to intravitreal aflibercept (IVA).
  • - Out of 43 patients analyzed, 32.6% experienced an extension of their treatment intervals by more than two weeks after switching to faricimab.
  • - Factors contributing to successful treatment extension included shorter dosing intervals prior to switching, the absence of polypoidal lesions, and thinner central choroidal thickness.
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  • Indocyanine green fluorescence angiography is a noninvasive imaging technique used to evaluate blood flow in tissues, particularly in infants suffering from conditions like necrotizing enterocolitis and midgut volvulus.
  • A study reviewed three infant patients who faced complications after surgery, highlighting instances where weak fluorescence indicated areas at risk for ischemia and inadequate blood supply.
  • The findings suggest that weak fluorescence can lead to significant postoperative issues, emphasizing the need for careful assessment during surgical procedures to avoid resection of non-viable intestinal segments.
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An 82-year-old man had been treated for lung adenocarcinoma and hepatocellular carcinoma (HCC). Contrast-enhanced computed tomography examination showed swelling of the left adrenal gland, suggesting metastasis of lung adenocarcinoma, HCC, or primary adrenal tumor. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) was performed for the pathological diagnosis, and adrenal metastasis of HCC was diagnosed.

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  • This clinical trial aimed to assess the safety and effectiveness of a time-intensified treatment strategy for high-risk neuroblastoma, involving delayed local surgery following aggressive chemotherapy.
  • Seventy-five patients were enrolled, with a 3-year progression-free survival rate of 44.4% and an overall survival rate of 80.7%, indicating a significant response to therapy without any deaths during treatment.
  • However, there were high rates of adverse effects, with 48% experiencing severe complications and 25% facing major surgical issues, suggesting more research is needed to confirm findings and improve safety.
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Introduction: Primary malignant melanoma of the esophagus is a very rare disease with a poor prognosis. We herein report a patient with primary malignant melanoma of the esophagus who underwent surgical resection.

Case Presentation: A 73-year-old female underwent an upper gastrointestinal endoscopy during follow-up for colonic diverticulitis.

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Bone regeneration is crucial for repairing bone tissue following various injuries. Research techniques that enable the study of metabolic changes in bone tissue under different conditions are important for understanding bone repair and remodeling. This study used bone scintigraphy to evaluate osteogenesis secondary to osteotomy in a preclinical model of New Zealand rabbits.

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Juxta-articular myxoma (JAM) is a rare soft tissue tumour predominantly composed of mucinous tissue and usually found around large joints. We report a 73-year-old woman with a 5-year history of a soft tissue mass in the thenar eminence of the right wrist who presented to our department. An initial diagnosis of a ganglion cyst was made using magnetic resonance imaging (MRI) and the jellied content of the mass by aspiration.

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Background: Although the incidence of os supranaviculare (OSSN) is generally low, symptomatic OSSN affects athletes. The aim of this study was to assess the variations of OSSN and the results of osteosynthesis between the OSSN and the navicular bone.

Methods: Eleven feet of 10 elite athletes with symptomatic OSSN were treated.

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  • This study compares respiratory function outcomes of patients who underwent thoracoscopic lobectomy (TS) versus those who had thoracotomy (TR) over a 12-year period.
  • The TR procedure was found to be quicker and performed on younger patients compared to TS, but both groups showed similar respiratory function results post-surgery after testing at age eight.
  • Despite the differences in procedure timing and duration, the pulmonary function test results (forced vital capacity and forced expiratory volume) were not significantly different between the two surgical methods.
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Liver metastasis in gastric cancer is incurable. Alpha-fetoprotein-producing gastric cancer has a poor prognosis and is prone to liver metastasis. We investigated the association between preoperative serum alpha-fetoprotein levels, liver metastasis, and expression of primitive enterocyte phenotype markers.

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Aim: To evaluate the efficacy of using the central venous (CV) port compared with peripheral intravenous access for contrast-material injection for contrast enhancement during the portal venous phase.

Materials And Methods: Patients were divided into three groups: CV delay, CV routine, and peripheral access (PA) groups. Patients in the CV delay group underwent injection in the arm-down position with an additional delay, while those in the CV routine and PA groups underwent injections with the routine injection protocol for portal venous phase imaging.

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Background: The quantification of hepatitis B virus (HBV) DNA is used to monitor antiviral treatment for HBV infection. Recently, an HBV-DNA quantification reagent and assay protocol have been developed for the µTASWako g1 (Fujifilm Wako Pure Chemical Corporation, Osaka, Japan), a fully automated genetic analyzer that uses PCR-capillary electrophoresis. We evaluated the performance of the newly developed µTASWako HBV-DNA assay using standard and clinical samples.

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  • A 64-year-old male with type 2 diabetes developed severe Ocular Cicatricial Pemphigoid (OCP) after taking a Dipeptidyl Peptidase-4 inhibitor for six years, presenting with persistent conjunctival inflammation and discharge.
  • Despite treatments and discontinuation of the DPP-4 inhibitor, his condition initially worsened, leading to various eye surgeries.
  • The study highlights the importance of thoroughly discussing medications in patients with ocular pemphigoid, especially those using DPP-4 inhibitors for diabetes management.
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  • Cancer is the leading cause of disease-specific death for children and AYAs in Japan, despite its rarity, prompting a study on treatment and incidence rates from 2016-2018.
  • Data from the National Cancer Registry revealed varying incidence rates, with 166.6 cases per million for children and 579 for AYAs, indicating different common cancer types based on age.
  • The majority of pediatric cases (20-30%) were treated at specialized pediatric cancer hospitals, while less than 10% of AYAs received care at these facilities, highlighting a need for improved cancer care systems.
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Diospyrobezoar is a relatively uncommon cause of small bowel obstruction. Here we report successful treatment in a patient with small bowel obstruction due to diospyrobezoar by laparoscopic-assisted surgery. A 93-year-old woman who had undergone distal gastrectomy and laparoscopic cholecystectomy presented with nausea and anorexia.

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  • Gastric pull-up is a procedure to reconnect the digestive tract after esophagectomy, but it can lead to issues like leakage and stricture due to gastric tube congestion.
  • A study compared outcomes between 117 patients who had esophagectomy, with 46 receiving standard treatment and 71 undergoing additional venous drainage.
  • Results showed that the superdrainage group experienced significantly fewer postoperative leaks (8.5% vs. 32.6%) and strictures (9.9% vs. 26.1%), suggesting that extra venous anastomosis is beneficial for recovery.
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A 57-year-old man visited our hospital for acute cholangitis due to common bile duct (CBD) stones in March 2021. Biliary stenting was performed without any complications. The cholangitis improved rapidly.

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