Inverse treatment planning for an electronic brachytherapy system delivering anisotropic radiation therapy.

An inverse radiation treatment planning algorithm for Sensus Healthcare's Sculptura electronic brachytherapy system has been designed. The algorithm makes use of simulated annealing to optimize the conformation number (CN) of the treatment plan. The highly anisotropic dose distributions produced by the Sculptura x-ray source empower the inverse treatment planning algorithm to achieve highly conformal treatment plans for a wide range of prescribed planning target volumes.