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[Study on three common mitochondrial DNA mutations in Leber's hereditary optic neuropathy].
Yun-xia Ma Yon-gan Zhou Jing-ping Zhang Quan-bin Zhang Wei-la Liu

Zhonghua Yi Xue Yi Chuan Xue Za Zhi

October 2012

Objective: To screen for genetic mutations in 35 patients with Leber's hereditary optic neuropathy (LHON).

Methods: Polymerase chain reaction and DNA sequencing were used to screen for the presence of mitochondrial DNA mutations.

Results: The total detection rate of top 3 common LHON mutations were 20.

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