Publications by authors named "Yomei Sakurai"
Chronotropic incompetence (CTI), the inability of the heart to increase its rate with increased activity, leads to exercise intolerance and predicts overall mortality. We previously reported that cardiac β-adrenergic receptor downregulation occurs in patients with CTI without heart failure (HF), indicating postsynaptic sympathetic nervous dysfunction. However, cardiac presynaptic sympathetic nervous system function in CTI is not fully understood.
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- - Spontaneous coronary artery rupture (SCAR) is a rare but serious condition that can be difficult to diagnose, as illustrated by a case involving a 70-year-old man who experienced sudden cardiac arrest.
- - Initial emergency coronary angiography (CAG) did not show any abnormalities, but subsequent surgery revealed that pericardial fluid was due to bleeding from the left circumflex artery (LCx).
- - A detailed review of the earlier CAG identified slight contrast leakage from the distal LCx, highlighting that SCAR should be considered in patients with unexplained pericardial effusion, and careful examination of CAG results is crucial.