Variability in Symptoms Complicates Utility of Case Definitions.

Background: Ambiguities in case definitions have created difficulties in replicating findings and estimating the prevalence rates for chronic fatigue syndrome (CFS) and Myalgic Encephalomyelitis (ME).

Purpose: The current study examined differences in occurrence rates for CFS and ME cardinal symptoms (i.e.

Chronic Fatigue Syndrome: Case Definitions and Diagnostic Assessment.

Chronic fatigue syndrome (CFS) is a chronic, debilitating illness that has posed considerable challenges for both patients and health care providers. Individuals with CFS often deal with considerable stigma and difficulties accessing appropriate care. Many medical professionals are increasingly recognizing the devastating nature of this illness, but at this time, few health care workers are knowledgeable and experienced enough to provide adequate patient care.