Publications by authors named "Yolanda Y Kwong"

Purpose: The purpose of this study is to compare the cost effectiveness of phacoemulsification and combined phacotrabeculectomy for lowering intraocular pressure (IOP) in primary angle closure glaucoma (PACG) eyes with coexisting cataract.

Methods: Real-life data of 2 previous randomized control trials that involved 51 medically uncontrolled PACG eyes and 72 medically controlled PACG eyes were utilized to calculate the direct cost of treatment. They were followed-up for 2 years.

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Article Synopsis
  • The study aims to identify clinical factors that lead to difficulty in controlling intraocular pressure (IOP) in patients with primary angle-closure glaucoma (PACG) undergoing cataract surgery.
  • The analysis included data from 123 PACG eyes treated either with phacoemulsification or phacotrabeculectomy, focusing on factors like preoperative IOP, use of glaucoma medications, and surgical methods.
  • Higher preoperative IOP and reliance on glaucoma drugs were significantly linked to treatment failure, with phacotrabeculectomy showing better results in controlling IOP compared to phacoemulsification.
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Purpose: To document the anatomical effects of clear lens extraction by phacoemulsification versus trabeculectomy on anterior chamber angle in patients with primary angle-closure glaucoma (PACG).

Methods: Gonioscopy and ultrasound biomicroscopy (UBM) were performed pre-operatively, and at 1 year after clear lens extraction or trabeculectomy in PACG eyes.

Results: Fifty PACG eyes of 50 patients were included.

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Objective: To compare phacoemulsification versus trabeculectomy with adjunctive mitomycin C in medically uncontrolled chronic angle-closure glaucoma (CACG) without cataract.

Design: Prospective, randomized clinical trial.

Participants: Fifty medically uncontrolled CACG eyes without cataract of 50 patients.

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Objective: To compare the complications of phacoemulsification alone vs combined phacotrabeculectomy in chronic angle-closure glaucoma (CACG) with coexisting cataract.

Methods: Patients with CACG with coexisting cataract recruited into 2 randomized controlled trials comparing phacoemulsification alone vs combined phacotrabeculectomy were pooled for analysis. The first trial recruited patients with medically controlled intraocular pressure, while the second trial recruited patients with medically uncontrolled intraocular pressure.

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Article Synopsis
  • The study aims to determine if simvastatin helps stabilize visual fields in patients with normal tension glaucoma.
  • The research involved 256 Chinese subjects monitored over 36 months, assessing visual field progression and various clinical factors.
  • Results showed that simvastatin users had a lower rate of visual field progression compared to non-users, suggesting it may have a protective effect against visual decline in these patients.
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Purpose: To investigate whether the presence of silent cerebral infarct (SCI) is related to field progression in patients with newly diagnosed normal-tension glaucoma (NTG).

Design: Prospective cohort study.

Participants: A total of 286 eyes from 286 NTG patients: 64 with SCI (SCI+) and 222 without SCI (SCI-).

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Purpose: To document anatomic effects of phacoemulsification versus combined phaco-trabeculectomy on drainage angle in primary angle closure glaucoma (PACG).

Methods: Indentation gonioscopy and ultrasound biomicroscopy were performed preoperatively, and then at 1 year after phacoemulsification alone or combined phaco-trabeculectomy in PACG patients.

Results: Seventy-two PACG eyes of 72 patients were included in this study.

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Article Synopsis
  • The study compared the effectiveness of phacoemulsification alone versus combined phacotrabeculectomy in patients with chronic angle closure glaucoma (CACG) and cataracts.
  • Results showed that combined surgery led to significantly lower intraocular pressure (IOP) and reduced the need for glaucoma medications over 24 months compared to phacoemulsification alone.
  • However, the combined approach also resulted in more postoperative complications and progression of optic neuropathy.
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Objective: To compare phacoemulsification alone versus combined phacotrabeculectomy in medically controlled chronic angle closure glaucoma (CACG) with coexisting cataract.

Design: Randomized clinical trial.

Participants: Seventy-two medically controlled CACG eyes with coexisting cataract.

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Purpose: To compare the efficacy of early phacoemulsification versus laser peripheral iridotomy (LPI) in the prevention of intraocular pressure (IOP) rise in patients after acute primary angle closure (APAC).

Design: Prospective randomized controlled trial.

Participants: Sixty-two eyes of 62 Chinese subjects, with 31 eyes in each arm.

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Purpose: To document the effect of a previous acute angle closure attack on the corneal endothelial cell density in chronic angle closure glaucoma (CACG) patients.

Methods: Consecutive cases of CACG with patent peripheral iridotomy had their central corneal endothelial cell density measured by specular microscopy. The corneal endothelial cell density of those CACG eyes with a previous documented acute angle closure attack were compared with those eyes without such a history, to determine the effect of a previous acute angle closure attack on corneal endothelial cell density.

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Article Synopsis
  • The study aimed to report on a surgical technique called microincision bimanual phacotrabeculectomy, aimed at treating patients with both glaucoma and cataracts.
  • It was conducted at the Glaucoma Service in Hong Kong Eye Hospital and involved using a small incision method that avoided trauma to the trabeculectomy site while implanting an intraocular lens.
  • Results showed a significant reduction in intraocular pressure and only a slight decrease in corneal endothelial cell count, with no major complications observed in the initial group within six months post-surgery, indicating that this technique is both effective and safe.
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Objective: To compare the visual outcomes and complication profiles of primary scleral-fixated intraocular lens (SFIOL) versus primary anterior chamber intraocular lens (ACIOL) implantation in cataract surgeries complicated by inadequate capsular support.

Design: Retrospective, interventional, comparative cases series.

Participants: Thirty-six eyes of 36 patients undergoing SFIOL implantation (group 1) and 46 eyes of 46 patients undergoing ACIOL implantation (group 2).

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Background: To describe the use of anterior segment optical coherence tomography (OCT) in imaging intrableb morphology after trabeculectomy.

Methods: 14 post-trabeculectomy eyes from 11 primary open angle glaucoma and 3 primary angle closure glaucoma subjects were studied. The blebs were classified with reference to slit lamp morphology and bleb function.

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Purpose: To evaluate the long-term clinical outcomes in eyes with retained presumed intraocular cotton fibers after cataract surgery.

Setting: Hong Kong Eye Hospital, Hong Kong, The People's Republic of China.

Methods: A retrospective review of 19 eyes with retained presumed intraocular cotton fibers after cataract surgery was performed.

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