Background: Most patients with haematological malignancies who undergo allogeneic haematopoietic stem cell transplant (HSCT) receive chemotherapy before the transplant to control the disease. Certain chemotherapy drugs can cause lung toxicity. Conversely, in patients with chronic respiratory conditions, the 6-min walking test (6MWT) and the desaturation-distance ratio (DDR) have demonstrated prognostic significance.
View Article and Find Full Text PDFBackground: The 6-min walking distance (6MWD) is often used to assess prognosis in pulmonary arterial hypertension (PAH) patients. Whether or not changes in arterial oxygen saturation (SpO) during exercise add prognostic value to the 6MWD in these patients is unclear. The objective of this study was to investigate if SpO changes during exercise adds prognostic value to the 6MWD in PAH patients.
View Article and Find Full Text PDFSARS-CoV-2 infection can cause a range of respiratory sequelae, especially in patients who have had severe Covid-19 pneumonia. Given the high number of patients who have developed this infection over a short period of time, numerous post-Covid-19 follow-up visits are being carried out, but no clinical follow-up protocol has been established to advise on the complementary tests to be performed and the frequency of these procedures. This consensus document was drawn up by professionals from different areas of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) in order to assist the clinician in identifying possible respiratory complications that may occur during the months following the acute disease, and to protocolize their follow-up and additional tests to be performed.
View Article and Find Full Text PDFBackground: The minimum controlling dose of treatment must be established in patients with asthma, but the outcome of step-down is unpredictable.
Objective: To identify factors associated with risk of control loss when stepping down asthma treatment and to develop a score to predict this risk.
Methods: A prospective, multicenter study including adults with well-controlled asthma was performed.