Publications by Yolanda Scuderi

Publications by authors named "Yolanda Scuderi"

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A Novel Liver-targeted Testosterone Therapy for Sarcopenia in Androgen Deprived Men With Prostate Cancer.

Handoo Rhee Anojan Navaratnam Irina Oleinikova Deborah Gilroy Yolanda Scuderi

J Endocr Soc

September 2021

Objective: Androgen deprivation therapy (ADT) reduces muscle and bone mass, increasing frailty in men with prostate cancer. The liver mediates the whole body anabolic effects of testosterone. Based on first-pass metabolism, liver-targeted testosterone treatment (LTTT) entails oral delivery of a small dose of testosterone that does not raise peripheral blood testosterone levels.

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