Nanosuspensions as carriers of active ingredients: Chemical composition, development methods, and their biological activities.

Nanosuspensions (NSps) are colloidal dispersions of particles that have the potential to solve the delivery problems of active ingredients associated with their low solubility in water or instability due to environmental factors. It is essential to consider their chemical composition and preparation methods because they directly influence drug loading, size, morphology, solubility, and stability; these characteristics of nanosuspensions influence the delivery and bioavailability of active ingredients. NSps provides high loading of drugs, protection against degrading agents, rapid dissolution, high particle stability, and high bioavailability of active ingredients across biological membranes.

Ultrasound-Assisted Extraction of Phenolic Compounds from Leaves: Optimization Using the Response Surface Methodology.

In this study, conditions for the ultrasound-assisted extraction (UAE) of soluble polyphenols from (PC) leaves were optimized using response surface methodology (RSM) by assessing the effect of extraction time (X = 2, 4, and 6 min), sonication amplitude (X = 60, 80, and 100%), and pulse cycle (X = 0.4, 0.7, and 1 s).

Current Situation and Perspectives of Fruit Annonaceae in Mexico: Biological and Agronomic Importance and Bioactive Properties.

The Annonaceae family is one of the oldest angiosperms. The genus is the one with the most species and, together with the only ones that contain edible fruits. In the last 10 years, interest in these fruit species has increased, mainly due to their nutritional properties and their application in the treatment of human diseases.