[Tuberculosis: Analysis of the history and development of multiple antibiotic resistance].

Tuberculosis is an ancient disease that has accompanied humanity for the last three thousand years and is considered the oldest infectious disease that still exists. The Mycobacterium tuberculosis bacillus was spread worldwide due to human migrations, and there is archaeological evidence of spinal tuberculosis cases in Egyptian and Andean mummies, as well as texts that attributed the disease to social factors before suspecting its infectious nature. Throughout its history, humans have dealt with this pathology by developing unusual and ineffective therapies, leading to a significant increase in the disease's mortality.