[Massive cardiac lipomatosis, an autopsy finding in a patient with sudden death].

The fat replacement of myocardial cells is a degenerative process that usually affects the right ventricle and is found in 50% of the elderly. The problem arises when this degeneration occurs to a massive degree, a differential diagnosis with other pathologies being necessary. We present the case of a patient who died suddenly and a massive cardiac lipomatosis was found on autopsy, as the only explanation of the outcome.

A controlled trial of the effects of leg training on breathing pattern and dynamic hyperinflation in severe COPD.

The effects of training on dynamic hyperinflation in stable chronic obstructive pulmonary disease (COPD) were investigated by using a controlled study of 28 subjects with FEV(1) = 42.5 (8.3 SD)%pred and 20 matched controls [FEV(1) = 44.

Dyspnea, ventilatory pattern, and changes in dynamic hyperinflation related to the intensity of constant work rate exercise in COPD.

Study Objective: We undertook the present study to investigate the perception of dyspnea (with respect to changes in end-inspiratory and end-expiratory lung volumes), during four different levels of high-intensity constant work rate exercise (CWRE) in patients with severe COPD.

Design: Crossover descriptive study with consecutively recruited subjects.

Setting: Tertiary university hospital.

Effects of training on the tolerance to high-intensity exercise in patients with severe COPD.

Background: There has been no systemic investigation of the effects of training on endurance at different high-intensity work rates in patients with COPD to date.

Objectives: We wanted to determine the effects of intense endurance training on tolerance to several high-intensity work rates and to establish the relationship between power (WR) and its tolerable duration (t) (t = W'/(WR - CP), being W', the curvature constant, thought to be reflective of anaerobic energy availability and/or tolerance to the uncomfortable sensations associated with the high-intensity exercise, and CP the critical power.

Methods: We studied 27 patients: age 62 +/- 5 years; FEV(1) 1.