Publications by authors named "Yoko Miyanari"
Article Synopsis
- BHLHE40 and BHLHE41 are transcription factors that influence cell behavior and are linked to the epithelial-to-mesenchymal transition (EMT), which is important in cancer progression.
- The study found that these factors are expressed differently depending on the disease stage in human endometrial cancer (HEC) and play a role in suppressing tumor cell invasion by inhibiting EMT-related proteins.
- BHLHE40 and BHLHE41 have a competitive relationship with the transcription factor SP1, which they regulate to control the expression of genes like TWIST1, suggesting they could serve as indicators of cancer aggressiveness and potential targets for treatment.
Homeodomain-only protein/not expressed in choriocarcinoma clone 1 (HOP/NECC1) is a newly identified gene that modifies the expression of cardiac-specific genes and thereby regulates heart development. More recently, HOP/NECC1 was reported to be a suppressor of choriocarcinogenesis. Here, we examined the temporal expression profile of HOP/NECC1 in wild-type mouse placenta.
View Article and Find Full Text PDFComplete hydatidiform moles (CHMs) are a type of androgenetic fertilization without an ovum. Cases of CHM exhibit a generalized swelling of the villi and are known to be highly associated with persistent disease or carcinoma. In contrast, partial hydatidiform moles (PHMs) also show characteristic hydropic changes among the villi, but the incidence of secondary disease is relatively low.
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