Publications by authors named "Yoko Katsuragawa-Taminishi"
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Synopsis of recent research by authors named "Yoko Katsuragawa-Taminishi"
- Yoko Katsuragawa-Taminishi's recent research focuses on the mechanisms of signaling pathways in hematological malignancies, specifically targeting key molecules involved in multiple myeloma and B-cell lymphomas to enhance therapeutic effectiveness.
- Significant findings include the identification of RSK2 and AKT as universal effectors downstream of PDPK1, leading to the exploration of TAS0612, a triple inhibitor that demonstrates robust anti-myeloma effects across varying cytogenetic abnormalities.
- The research also delves into the role of the miR-17-92 cluster in mantle cell lymphoma, revealing its dependence on specific transcription factors and chromatin modifications to regulate B-cell receptor signaling, thereby contributing to the understanding of the disease's pathogenic mechanisms.