Pathologic investigation failure of trabeculotomy.

Purpose: To investigate the reason for failure of trabeculotomy using trabeculectomy (TLE) specimens involving the area of previous trabeculotomy.

Materials And Methods: Thirteen TLE specimens from 13 patients with open-angle glaucoma were processed for transmission electron microscopy and light microscopy, involving immunohistochemical staining of thrombomodulin, D2-40 (podoplanin), and CD34.

Results: All intraocular pressure after trabeculotomy decreased to normal and then returned to the same or a higher level compared with that before TLE.