Publications by authors named "Yoichiro Nakajima"

BACKGROUND Periodontal disease and rheumatoid arthritis (RA) are closely related, and periodontal therapy can potentially improve RA activity. However, it is not clear in which RA patient populations are more effective periodontal therapy for RA treatment. This study aimed to evaluate the effects of treatment for periodontal disease in 30 patients with rheumatoid arthritis and the titers of antibodies to Porphyromonas gingivalis (P.

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Additive manufacturing techniques are being used in the medical field. Orthopedic hip prostheses and denture bases are designed and fabricated based on the patient's computer-aided design (CAD) data. We attempted to incorporate this technique into dental implant bone augmentation.

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In the field of oral and maxillofacial surgery, establishment of a new method for predicting morphology is desirable. Therefore, the purpose of the present study was to establish a new method for predicting the original shape of a mandibular defect site using the homologous modeling technique. This study used data from 44 patients who underwent computed tomography in the Department of Oral Surgery at Osaka Medical College.

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Background: Parotid cancer is relatively rare, and malignancy varies; therefore, novel markers are needed to predict prognosis. Recent advances in matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS), useful for visualization of lipid molecules, have revealed the relationship between cancer and lipid metabolism, indicating the potential of lipids as biomarkers. However, the distribution and importance of phospholipids in parotid cancer remain unclear.

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Jaw reconstruction using an additive-manufacturing titanium artificial bone (AMTAB) has recently attracted considerable attention. The synthesis of a titanium artificial bone is based on three-dimensional computed tomography images acquired before surgery. A histological evaluation of porous AMTAB (pAMTAB) embedded in rat calvarial bone defects was conducted.

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Grit-blasted/acid-etched titanium dental implants have a moderately roughened surface that is suitable for cell adhesion and exhibits faster osseointegration. However, the roughened surface does not always maintain stable fixation over a long period. In this study, a simple heat treatment at 600°C was performed on a commercially available dental Ti implant with grit-blasting/acid-etching, and its effect on mineralization capacity was assessed by examining apatite formation in a simulated body fluid (SBF).

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Selective laser melting (SLM) is a promising technology capable of producing individual characteristics with a high degree of surface roughness for implants. These surfaces can be modified so as to increase their osseointegration, bone generation and biocompatibility, features which are critical to their clinical success. In this study, we evaluated the effects on preosteoblast proliferation and differentiation of titanium metal (Ti) with a high degree of roughness (Ra = 5.

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Article Synopsis
  • The study explores the effectiveness of a mixed-acid and heat (MAH) treatment on titanium plates produced through additive manufacturing (AM) to enhance their compatibility with bone.
  • AM titanium plates were custom-made to fit rat calvarial bones and implanted, with one group receiving the MAH treatment while the other remained untreated.
  • Results showed that MAH-treated plates had significantly stronger mechanical bonding and improved bone formation compared to untreated plates, indicating the treatment enhances the osteogenic properties of AM titanium.
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Objectives: Recently, the oral microbiome has been found to be associated with oral and general health status. Although various oral sample collection protocols are available, the potential differences between the results yielded by these protocols remain unclear. In this study, we aimed to determine the effects of different time points and methods of oral sample collection on the outcomes of microbiome analysis.

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Objective: In the field of forensic science, sex discrimination of skeletons is an important identification item for personal identification. The individual sex discrimination method using skeletons includes a determination method using measurement values and a macroscopic form observation method. Both methods have advantage and disadvantage.

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We have encountered a rare case in which the subject underwent maxillary sinus floor elevation at another hospital, and a screw to fix the grafted bone substitute was forced into the maxillary sinus and intruded into the bone. Various different foreign bodies have been reported as being forced into the maxillary sinus due to dental treatment, and these foreign bodies are often retained on the maxillary sinus mucous membrane. However, no reports have described a screw forced in and intruded into the peculiar position in the bone, as seen in the present case, which we report here with additional discussion.

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Introduction: In mandibular reconstruction, repositioning the mandibular position is still challenging and time consuming. We invented a new re-positioning technique using a resin plate combined with a reconstructive plate in reconstructing the mandible with an osteocutaneous free flap. The purpose of this report is to introduce this technique and evaluate the accuracy of mandibular reconstruction using free flaps.

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Article Synopsis
  • - Bone augmentation is a procedure that addresses bone defects in dental implant treatments by using a prosthetic material covered with a titanium mesh that is shaped to fit the defect.
  • - The Selective Laser Melting (SLM) method allows for the customization of the titanium mesh based on preoperative CT scans, resulting in quicker surgeries and better bone shape regeneration compared to traditional methods.
  • - In two case studies using the SLM titanium mesh, both patients healed without complications, suggesting this method could be a promising option for bone augmentation in dental implants.
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The practical use of additive manufacturing to create artificial bone as a material for repairing complex bone defects is currently attracting attention. In this study, we compared the osteogenic capacity of materials composited by the method developed by Kokubo of treating 3D-printed titanium (Ti) mesh with a mixture of HSO and HCl and heating (mixed-acid and heat treatment) with that of materials subjected to conventional chemical treatment. Ti plates treated with this method have been found to promote highly active bone formation on their surface when inserted into rabbit tibial bone defects.

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Introduction: The evaluation of bone quality at the site of the alveolar bone for a dental implant is very important. This study presents an easy technique for direct evaluation of alveolar bone quality using nondecalcified cryofilm frozen sections on human alveolar bone core samples.

Materials And Methods: Core samples harvested from alveolar bone were immediately frozen in cooled hexanen and slowly cut using a disposable tungsten carbide blade; the sliced sections were collected with adhesive cryofilms.

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