Publications by authors named "Yoichi Toyoda"
Article Synopsis
- Erythritol, a sugar alcohol, has been found to inhibit the growth of a specific staphylococcus strain (JCM7470) and other strains isolated from dogs with pyoderma.
- The study showed that erythritol increases the expression of genes responsible for sugar uptake (PTS genes), indicating a molecular mechanism behind its growth inhibition effects.
- Additionally, the presence of glucose can restore the growth of these staphylococcus strains, suggesting that a lack of glucose may play a significant role in the growth inhibition caused by erythritol.
The strong bond between dogs and their owners creates a close association that could result in the transfer of antibiotic-resistant bacteria from canines to humans, potentially leading to the spread of antimicrobial resistance genes. , a common causative agent of persistent ear infections in dogs, is often resistant to multiple antibiotics. Assessing the antimicrobial resistance profile and genotype of is crucial for the appropriate use of veterinary pharmaceuticals.
View Article and Find Full Text PDFBackground: Streptococcus canis causes deep pyoderma in canines, which raises concerns about the risk of isolates from lesions acquiring an antibiotic-resistant phenotype. It is necessary to identify effective antibiotics and the characteristics of the pathogenic cluster for S. canis-associated deep pyoderma.
View Article and Find Full Text PDFBackground: Antimicrobial resistance in Staphylococcus pseudintermedius (SP) and the prevalence of meticillin-resistant SP (MRSP) is increasing in dogs worldwide.
Objectives: To evaluate the influence of hospital size on antimicrobial resistance of SP and whether restricted use of antimicrobials based on antibiograms could reduce the identification of antimicrobial resistance in SP from infected dogs.
Methods And Materials: In Study 1, a total of 2,294 SP isolates from dogs with pyoderma (n = 1,858, 52 hospitals) or otitis externa (OE; n = 436, 44 hospitals) taken between 2017 and 2019 were analysed.
Background: Cefovecin has been widely used to treat skin infections in dogs. The relationship of the cefovecin disk-diffusion test results to the presence of the mecA gene and the clinical efficacy of cefovecin have not been fully evaluated.
Hypothesis/objectives: To determine the usefulness of an in vitro cefovecin disk-diffusion test in predicting the presence of the mecA gene in Staphylococcus pseudintermedius, as well as the in vivo efficacy of cefovecin therapy in dogs with superficial pyoderma.