Publications by authors named "Yohanna Carvalho Dos Santos Aoun Chikhani"
In Vitro and In Vivo Synergism of Fosfomycin in Combination with Meropenem or Polymyxin B against KPC-2-Producing Clinical Isolates.
Aghata Cardoso da Silva Ribeiro Yohanna Carvalho Dos Santos Aoun Chikhani Tiago Barcelos Valiatti André Valêncio Mariana Neri Lucas Kurihara
Antibiotics (Basel)
January 2023
Fosfomycin disodium is a potential therapeutic option to manage difficult-to-treat infections, especially when combined with other antimicrobials. In this study, we evaluated the activity of fosfomycin in combination with meropenem or polymyxin B against contemporaneous KPC-2-producing clinical isolates (KPC-KPN). Synergistic activity was assessed by checkerboard (CKA) and time-kill (TKA) assays.
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