Publications by authors named "Yohann Cout"
Article Synopsis
- Sexual reproduction of parasites in cats is not well-studied due to ethical issues with using cats for research, particularly focused on the small intestine.
- The study identifies transcription factors AP2XII-1 and AP2XI-2, which play a critical role in regulating gene expression during the lifecycle of the parasite—specifically, they silence genes needed for merozoite development, which is essential for sexual reproduction and transferring the parasite to new hosts.
- By conditionally depleting these transcription factors, researchers can trigger a switch from the tachyzoite stage to the merozoite stage, facilitating a deeper understanding of sexual reproduction and leading to potential treatments to prevent transmission of the parasite.
