Publications by authors named "Yohan Brito Kevorkian"
Evidences of HEV genotype 3 persistence and reactivity in liver parenchyma from experimentally infected cynomolgus monkeys (Macaca fascicularis).
Diana Chaves Pereira Mejido Jaqueline Mendes de Oliveira Ana Maria Coimbra Gaspar Noemi Rovaris Gardinali Fernanda de Oliveira Bottino Yohan Brito Kevorkian
PLoS One
February 2020
Article Synopsis
- HEV-3 is a zoonotic virus causing acute hepatitis E, and primate models help study its effects.
- Eight cynomolgus macaques were inoculated with HEV-3 to analyze the viral impact over 67 days, revealing a complex recovery phase.
- While some biochemical signs normalized by 55 days, lingering HEV RNA and antigen were found in organs afterwards, suggesting the potential for chronic infections and risks in liver transplants.