Synopsis of recent research by authors named "Yohan Bosse"
- Yohan Bosse's recent research primarily focuses on the genetic and molecular underpinnings of lung cancer and other pulmonary diseases, utilizing advanced methodologies such as genome-wide association studies (GWAS) and metabolomic profiling to identify key susceptibility loci and potential biomarkers for diagnosis and treatment.
- His studies address critical issues in lung cancer risk stratification, particularly the differentiation of genetic factors from smoking behaviors, as evidenced by comprehensive analyses of large, diverse cohorts and the development of polygenic risk scores (PRS).
- Additionally, Bosse’s work explores the broader implications of genetic risk on lung function and cardiac health through models that assess the interaction between genetic factors, environmental influences (like smoking), and their respective roles in diseases such as pulmonary neuroendocrine neoplasms and mitral valve prolapse.