Background: The increase of glucose transport is a distinguishing marker of tumor cells. We hypothesized that a hypopharyngeal carcinoma, characterized by high frequency of lymph node spread or distant metastasis, was associated with glucose transporter 1 (Glut 1) overexpression.
Materials And Methods: We investigated the incidence of Glut1 expression by immunostaining in 99 patients with hypopharyngeal carcinoma, and revealed the correlation with the clinical characteristics.
Background: Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis, which is associated with tumor progression or metastasis.
Patients And Methods: Immunohistochemical analysis was performed in 109 patients with tongue squamous cell carcinoma. Cox's proportional hazards regression analysis was used to identify the multivariate predictive value of the prognostic factors.