Publications by authors named "Yogev Cohen"

Article Synopsis
  • The study aimed to investigate the incidence and significance of isolated PR prolongation (IPRP) after transcatheter aortic valve implantation (TAVI), particularly without accompanying QRS changes on ECG.
  • Out of 1108 patients, 146 exhibited IPRP, and their clinical outcomes, including the need for pacemakers and overall mortality, were compared with 290 patients without ECG changes post-TAVI.
  • Results indicated that IPRP in patients with narrow QRS was not linked to negative outcomes, suggesting that doctors may take a more lenient approach toward treating these patients.
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Over the past two decades there have been significant developments in the fields of laboratory technology, genetics and bioinformatics. These developments have raised the attractiveness of liquid biopsy - a test aimed to detect tumor markers in body fluids. One of the liquid biopsy methods is based on identification of circulating tumor DNA - fragments of DNA originating from the tumor which are evident in the bloodstream - revealing the various tumor characteristics via simple blood tests.

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The likelihood of recurrence in breast cancer patients with hormone receptor-positive (HR-positive) tumors is influenced by clinical, histopathological, and molecular features. Recent studies suggested that activated STAT3 (pSTAT3) might serve as a biomarker of outcome in breast cancer patients. In the present work, we have analyzed the added value of pSTAT3 to OncotypeDx Recurrence Score (RS) in patient prognostication.

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Background: Germline pathogenic variant (PV) carriers have high lifetime risk of developing breast cancer and therefore subjected to intense lifetime screening. However, solid data on the effectiveness of high-risk screening of the carrier population is limited.

Patients And Methods: Retrospectively, we analyzed 346 women diagnosed with breast tumors.

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