A 'twist' in the tale of a 'simple' laparoscopic cholecystectomy: Duplication of the gall bladder.

The duplication of the gall bladder (GB) is unusual biliary anatomy that can be encountered during cholecystectomy and can create intraoperative confusion if missed on pre-operative imaging. Here, we describe a case of duplication of GB in a young female, which was detected during laparoscopic cholecystectomy as an operative surprise. Laparoscopic cholecystectomy was done successfully with the removal of both the GBs.

Computational fluid dynamics-based disease transmission modeling of SARS-CoV-2 Intensive Care Unit.

Covid-19 has become one of the most severe diseases causing acute respiratory problems and has killed millions of people worldwide. It was declared as the ongoing pandemic by the World Health Organization. It is an infectious virus which can be transmitted by sneezing, coughing and exhalation of air by any infected person.

Application of RP-HPLC method in dissolution testing and statistical evaluation by NASSAM for simultaneous estimation of tertiary combined dosages forms.

A dissolution method with robust high performance liquid chromatographic (HPLC) analysis for immediate release tablet formulation was developed and validated to meet the requirement as per International Conference on Harmonization (ICH) and United States Food and Drug Administration (USFDA) guidelines. The method involved the use of Agilent ZORBAX Eclipse XDB C column, and temperature was maintained at 30 °C. After optimization, the mobile phase was selected as phosphate buffer (KHPO, 30 mM) : ACN (60:40, v/v) with pH 3.

Management of oral submucous fibrosis by different surgical approaches: report of three cases.

Oral submucous fibrosis (OSMF) is an insidious chronic progressive disease of the oral cavity which is considered as a precancerous condition. The suggested aetiological factor is the practice of certain customs/habits of the inhabitants of South East Asia. As the disease progresses, the oral mucosa becomes stiff due to the formation of fibrotic bands in the cheek, ultimately leading to reduced mouth opening and trismus.