Publications by authors named "Yogesh Sean Gupta"

Objective: To investigate the relationship between α-antitrypsin deficiency (AATD), a disorder resulting in protease activity imbalances, and the risk of ascending aortic aneurysm.

Methods: In this single-center study, from August 1, 2018, to February 25, 2019, demographic data were retrospectively collated for patients with AATD-associated emphysema (AATD group) or non-AATD-associated emphysema (control group) with available high-resolution computed tomography scans. Mean ascending aortic diameter was compared between the groups, and the correlation of diameter with age was analyzed.

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  • A study aimed to develop a deep learning algorithm to predict the severity of COVID-19 based on chest radiographs and clinical outcomes.
  • It analyzed data from 338 patients aged 21-50 and trained the algorithm with information from both imaging and existing clinical variables.
  • Results showed that combining radiograph findings with clinical data significantly improved predictions for patient outcomes like intubation and survival rates.
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  • - Recent research indicates that coronary artery calcification (CAC) can help predict severe outcomes in COVID-19 patients, particularly with comorbid cardiovascular disease.
  • - In a study of 180 COVID-19 patients, those with detected CAC were significantly more likely to require intubation or face mortality, with severe CAC showing even higher risks.
  • - The study concluded that both the severity of CAC and the number of arteries affected correlated with worse outcomes, while prior surgeries like coronary artery bypass grafting or stenting did not significantly impact patient mortality or intubation rates.
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Purpose: We describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastinum (SPM) in the absence of prior mechanical ventilation.

Materials And Methods: A total of 11 non-intubated COVID-19 patients (8 male and 3 female, median age 61 years) developed SE and SPM between March 15 and April 30, 2020 at a multi-center urban health system in New York City. Demographics (age, gender, smoking status, comorbid conditions, and body-mass index), clinical variables (temperature, oxygen saturation, and symptoms), and laboratory values (white blood cell count, C-reactive protein, D-dimer, and peak interleukin-6) were collected.

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Background Chest radiography has not been validated for its prognostic utility in evaluating patients with coronavirus disease 2019 (COVID-19). Purpose To analyze the prognostic value of a chest radiograph severity scoring system for younger (nonelderly) patients with COVID-19 at initial presentation to the emergency department (ED); outcomes of interest included hospitalization, intubation, prolonged stay, sepsis, and death. Materials and Methods In this retrospective study, patients between the ages of 21 and 50 years who presented to the ED of an urban multicenter health system from March 10 to March 26, 2020, with COVID-19 confirmation on real-time reverse transcriptase polymerase chain reaction were identified.

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Purpose: The main purpose of the study is to determine if the presence of a particular computed tomography (CT) imaging finding, a bursal lipohematoma, portends the presence of a concomitant rotator cuff tear (RCT) in patients with proximal humerus fractures by reviewing previous CTs.

Methods: Three hundred eighty-six CT scans were retrospectively reviewed by two board-certified radiologists to determine the presence of a proximal humerus fracture and to assess for the presence of a subacromial/subdeltoid or subcoracoid bursal hematoma. The medical record including operative documentation was then examined in the patients with proximal humerus fractures, with or without a concomitant bursal lipohematoma.

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