Designing, Validation, and Feasibility of Integrated Approach of Heartfulness Meditation and Yoga Protocol (IAHFNM & YP) for Hypertensive Participants.

The module was designed and developed at Heartfulness Institute, Kanha Shanti Vanam, Hyderabad. The Department of Medicine, MGM Medical College & Hospital, MGMIHS, Navi Mumbai, carried out the validation and subsequently pilot-tested on volunteers. Forty experts were selected to validate the contents of IAHFNM & YP which was designed after a thorough review of meditation and yoga literature.

Effect of Heartfulness Meditation on Oxidative Stress and Mindfulness in Healthy Participants.

Background: Mental health issues are a major cause of poor life outcomes. Heartfulness (HFN) meditation is recommended for stress management and daily awareness. Although studies have shown that HFN can improve burnout and well-being, the biological mechanism underlying oxidative stress markers in a healthy human is unclear.

Exploring the neuropharmacological properties of scopoletin-rich extract using and methods.

Objectives: This study investigates the neuropharmacologic properties of Scopoletin, a bioactive compound in (EA) extract, for managing cognitive impairment using , , and zebrafish embryo toxicity assays.

Methods: The study estimates Scopoletin concentration in EA extract using HPTLC, assesses antioxidant properties using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing ability of plasma (FRAP) assays, and uses bioinformatic tools for scopoletin targets. Zebrafish embryo toxicity (ZET) is used to assess its toxicological profile.

Resolving the topology of encircling multiple exceptional points.

Non-Hermiticity has emerged as a new paradigm for controlling coupled-mode systems in ways that cannot be achieved with conventional techniques. One aspect of this control that has received considerable attention recently is the encircling of exceptional points (EPs). To date, most work has focused on systems consisting of two modes that are tuned by two control parameters and have isolated EPs.

Pyrolysis Characteristics and Determination of Kinetic and Thermodynamic Parameters of Raw and Torrefied Chinese Fir.

Torrefaction influences the structural and physicochemical properties of biomass, thus further altering its thermal degradation behavior. In this study, the pyrolysis characteristics, reaction kinetics, and thermodynamic parameters of raw and torrefied Chinese fir (CF) were investigated. The torrefaction was conducted at 220 °C (mild) and 280 °C (severe), the pyrolysis was performed from ambient temperature to 600 °C, and four different heating rates (i.

Impact of Heartfulness meditation practice on anxiety, perceived stress, well-being, and telomere length.

Objective: Exhaustion, stress, and burnout have all been found to be reduced using techniques like yoga and meditation. This study was carried out to check the effectiveness of Heartfulness practice (a form of meditation) on certain psychological and genetic variables.

Methods: A total of 100 healthy individuals (aged 18-24) were recruited and randomized into two groups-Heartfulness intervention and control group.

Hybrid hydrodynamic cavitation (HC) technique for the treatment and disinfection of lake water.

Water reclamation from lakes needs to be accomplished efficiently and affordably to ensure the availability of clean, disinfected water for society. Previous treatment techniques, such as coagulation, adsorption, photolysis, ultraviolet light, and ozonation, are not economically feasible on a large scale. This study investigated the effectiveness of standalone HC and hybrid HC + HO treatment techniques for treating lake water.

Microbial Population Dynamics in Lemnaceae (Duckweed)-Based Wastewater Treatment System.

The dynamic microflora associated within, and in the surrounding aquatic environment, has been found to be responsible for the functional properties of many aquatic plants. The aim of the current work was to evaluate the effectiveness of Lemnaceae-based wastewater treatment system under tropical conditions and investigate the changes in the aquatic microflora upon plant growth. A biological wastewater treatment system was designed and investigated using mixed Lemnaceae culture comprising Lemna minor and Spirodela polyrhiza in a batch mode.

Automobile service station waste assessment and promising biological treatment alternatives: a review.

Unprecedented growth in the automobile sector has led to an increased number of automobile service stations across all major cities especially in the developing countries. These service stations release huge amounts of waste that contain objectionable levels of oil and grease (O&G) and heavy metals, amongst other environmentally toxic compounds. Not much literature is available on the hazardous nature, public health concerns, and sustainable treatment options of such an industrial waste.

Measuring the knot of non-Hermitian degeneracies and non-commuting braids.

Any system of coupled oscillators may be characterized by its spectrum of resonance frequencies (or eigenfrequencies), which can be tuned by varying the system's parameters. The relationship between control parameters and the eigenfrequency spectrum is central to a range of applications. However, fundamental aspects of this relationship remain poorly understood.

Isolation and development of a microbial consortium for the treatment of automobile service station wastewater.

Aim: This work aims to investigate the nature of waste being generated by automobile service stations (ASS) and to devise a microbial-based formulation for the treatment of ASS wastewater.

Methods And Results: Analysis of soil and water samples from the vicinity of different ASS in and around the Pune city region (India) revealed the presence of significant amounts of many heavy metals including zinc (Zn) 13.8-175.

Employing waste to manage waste: Utilizing waste biomaterials for the elimination of hazardous contaminant [Cr(VI)] from aqueous matrices.

Pollution caused due to discharge of toxic and hazardous chemical contaminants from industrial processes is an issue of major environmental concern. Hexavalent chromium [Cr(VI)] is one such known toxic heavy metal contaminant emanated largely from various industrial processes. Since physical-chemical treatment techniques are beset with several problems, there is an increased attention on the use of waste biomaterials/biomass as sorbents for the elimination of heavy metals from aqueous matrices.

Biomanagement of hexavalent chromium: Current trends and promising perspectives.

Chromium (Cr) is most widely used heavy metal with vast applications in industrial sectors such as metallurgy, automobile, leather, electroplating, etc. Subsequently, these industries discharge large volumes of toxic Cr containing industrial wastewaters without proper treatment/management into the environment, causing severe damage to human health and ecology. This review gives some novel insights on the existing, successful and promising bio-based approaches for Cr remediation.

Indeterminate growth of the umbel inflorescence and bulb is associated with increased expression of the TFL1 homologue, AcTFL1, in onion.

TERMINAL FLOWER1 (TFL1) is a key gene for maintenance of vegetative and inflorescence indeterminacy and architecture. In onion, flowering and bulbing are two distinct developmental phases, each under complex environmental regulatory control. We have identified two CEN/TFL1-like genes from onion designated as AcTFL1 and AcCEN1.

Synthesis and biological evaluation of some new tricyclic pyrrolo[3,2-e]tetrazolo[1,5-c]pyrimidine derivatives as potential antitubercular agents.

A series of new tricyclic pyrrolo[3,2-e]tetrazolo[1,5-c]pyrimidines 8a-l were synthesized and characterized by IR, NMR ( H and C), and mass spectral analysis. The newly synthesized compounds 8a-l were inspected for their in vitro antitubercular activity against Mycobacterium tuberculosis (MTB) H Ra using an established XTT reduction menadione assay (XRMA). The title compounds exhibited minimum inhibitory concentrations (MIC ) ranging from 0.

A Novel Poly(vinylidene fluoride)-Based 4-Miktoarm Star Terpolymer: Synthesis and Self-Assembly.

A well-defined amphiphilic miktoarm polymer incorporating poly(vinylidene fluoride) (PVDF), polystyrene (PS), and poly(ethylene glycol) (PEG) blocks was synthesized via a combination of atom-transfer radical polymerization (ATRP), iodine transfer radical polymerization (ITP), and copper-catalyzed azide-alkyne cycloaddition (CuAAC). Morphology and self-assembly of this star polymer were examined in organic solvents and in water. The aggregates formed in water were found to possess unusual frustrated topology due to immiscibility of PS and PVDF.

Well-defined multiblock poly(vinylidene fluoride) and block copolymers thereof: a missing piece of the architecture puzzle.

Unprecedented synthesis of multiblock poly(vinylidene fluoride) (PVDF, up to 16 300 g mol) with narrow-dispersity blocks (Đ = 1.26) mediated by a fluorinated cyclic xanthate via reversible addition-fragmentation chain transfer (RAFT) polymerization is reported. The as-synthesized multiblock PVDF was employed as a macroRAFT agent to prepare valuable multiblock copolymers with potential applications in emerging areas.

Bio-affinity of copper(II) complexes with nitrogen and oxygen donor ligands: Synthesis, structural studies and in vitro DNA and HSA interaction of copper(II) complexes.

Reported herein the binding affinity between Human Serum Albumin and the DNA binding and cleavage activity of three copper(II) complexes, [Cu(phen)(o-van)ClO] (1), [Cu(phen)(gly)]ClO (2) and [Cu(L)(HO)] (3) wherein 1 and 2 are synthesized with 1,10-phenanthroline (phen) and co-ligands (o-van: o-vanillin; gly: glycine) and 3 with a ligand 2-hydroxy-3-methoxybenzylidene-4H-1,2,4-triazol-4-amine (HL). Complex 2 crystallizes in monoclinic (P21/n) space group shows square pyramidal geometry. The complex 3 crystallizes in monoclinic (P21/a) space group.

Crystal structure of Zn(ZnCl)(Cho): the transformation of ions to neutral species in a deep eutectic system.

A neutral molecular complex, Zn(ZnCl)(Cho), has been isolated from the well-known choline chloride/ZnCl deep eutectic system (DES) and its crystal structure has been determined. The structure demonstrates the possibility of isolating unusual coordination complexes from DES which departs from the well-established observation of such systems being formed from large, ionic metal complexes or oligomers.

Versatility of Two Diimidazole Building Blocks in Coordination-Driven Self-Assembly.

A series of discrete molecular architectures was synthesized via self-assembly of two "linear" diimidazole donors [L1 = 1,4-di(1H-imidazol-1-yl)benzene and L2 = 1,1'-(2,5-dimethyl-1,4-phenylene)bis(1H-imidazole)] independently with cis-[(tmeda)Pd(NO)] [tmeda = N,N,N',N'-tetramethylethane-1,2-diamine], cis-[(tmeda)Pt(NO)], a diplatinum(II) acceptor (bisPt), and Pd(NO). The donors L1 and L2 are isostructural with four hydrogens in the benzene ring of L1, whereas in L2 two of such hydrogens are substituted by methyl groups. The assemblies were characterized by NMR spectroscopy and electrospray ionization mass spectrometry analyses along with single-crystal structure determination of three of them.

Embryonic Zebrafish Model - A Well-Established Method for Rapidly Assessing the Toxicity of Homeopathic Drugs: - Toxicity Evaluation of Homeopathic Drugs Using Zebrafish Embryo Model.

Objectives: Advancements in nanotechnology have led to nanoparticle (NP) use in various fields of medicine. Although the potential of NPs is promising, the lack of documented evidence on the toxicological effects of NPs is concerning. A few studies have documented that homeopathy uses NPs.

Versatile Reactivity and Theoretical Evaluation of Mono- and Dinuclear Oxidovanadium(V) Compounds of Aroylazines: Electrogeneration of Mixed-Valence Divanadium(IV,V) Complexes.

The substituted hydrazones H2L(1-4) (L(1-4) = dibasic tridentate ONO(2-) donor ligands) obtained by the condensation of 2-hydroxy-1-naphthaldehyde and 2-aminobenzoylhydrazine (H2hnal-abhz) (H2L(1)) , 2-hydroxy-1-naphthaldehyde and 2-hydroxybenzoylhydrazine (H2hnal-hbhz) (H2L(2)), 2-hydroxy-1-acetonaphthone and benzoylhydrazine (H2han-bhz) (H2L(3)), or 2-hydroxy-1-acetonaphthone and 2-aminobenzoylhydrazine (H2han-abhz) (H2L(4)) are prepared and characterized. Reaction of ammonium vanadate with the appropriate H2L(1-4) results in the formation of oxidoethoxidovanadium(V) [V(V)O(OEt)(L(1-4))] (1-4) complexes. All compounds are characterized in the solid state and in solution by spectroscopic techniques (IR, UV-vis, (1)H, (13)C, and (51)V NMR, and electrospray ionization mass spectrometry).

Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu(I/II) complexes of thiosemicarbazone: special emphasis on their interactions with DNA.

4-(p-X-phenyl)thiosemicarbazone of napthaldehyde {where X = Cl (HL¹) and X = Br (HL²)}, thiosemicarbazone of quinoline-2-carbaldehyde (HL³) and 4-(p-fluorophenyl)thiosemicarbazone of salicylaldehyde (H₂L⁴) and their copper(I) {[Cu(HL¹)(PPh₃)₂Br]·CH₃CN (1) and [Cu(HL²)(PPh₃)₂Cl]·DMSO (2)} and copper(II) {[(Cu₂L³₂Cl)₂(μ-Cl)₂]·2H₂O (3) and [Cu(L⁴)(Py)] (4)} complexes are reported herein. The synthesized ligands and their copper complexes were successfully characterized by elemental analysis, cyclic voltammetry, NMR, ESI-MS, IR and UV-Vis spectroscopy. Molecular structures of all the Cu(I) and Cu(II) complexes have been determined by X-ray crystallography.

Synthesis, characterization and reactivity studies of electrophilic ruthenium(II) complexes: a study of H₂ activation and labilization.

Reaction of 2,2'-bipyridine (bpy) with dinuclear complexes [RuCl(dfppe)(μ-Cl)3Ru(dmso-S)3] (dfppe = 1,2-bis(dipentafluorophenyl phosphino)ethane (C6F5)2PCH2CH2P(C6F5)2; dmso = dimethyl sulfoxide) (1) or [RuCl(dfppe)(μ-Cl)3RuCl(dfppe)] (2) affords the mononuclear species trans-[RuCl2(bpy)(dfppe)] (3). Using this precursor complex (3), a series of new cationic Ru(II) electrophilic complexes [RuCl(L)(bpy)(dfppe)][Z] (L = P(OMe)3 (5), PMe3 (6), CH3CN (7), CO (8), H2O (9); Z = OTf (5, 6, 7, 8), BAr(F)4 (9) have been synthesized via abstraction of chloride by AgOTf or NaBAr(F)4 in the presence of L. Complexes 5 and 6 were converted into the corresponding isomeric hydride derivatives [RuH(PMe3)(bpy)(dfppe)][OTf] (10a, 10b) and [RuH(P(OMe)3)(bpy)(dfppe)][OTf] (11a, 11b) respectively, when treated with NaBH4.

Syntheses and structural investigation of some alkali metal ion-mediated LV(V)O2(-) (L(2-) = tridentate ONO ligands) species: DNA binding, photo-induced DNA cleavage and cytotoxic activities.

Eight alkali metal ion-mediated dioxidovanadium(v), [{V(V)O2L(1-6)}A(H2O)n]∝, complexes for A = Li(+), Na(+), K(+) and Cs(+), containing tridentate aroylhydrazonate ligands coordinating via ONO donor atoms, are described. All the synthesised ligands and the metal complexes were successfully characterised by elemental analysis, IR, UV-Vis and NMR spectroscopy. X-ray crystallographic investigation of 3, 5-7 shows the presence of distorted NO4 coordination geometries for LVO2(-) in each case, and varying μ-oxido and/or μ-aqua bridging with interesting variations correlated with the size of the alkali metal ions: with small Li(+), no bridging-O is found but four ion aggregates are found with Na(+), chains for K(+) and finally, layers for Cs(+).