Publications by authors named "Yoav Zaltsman"
Nucleic Acids Res
December 2017
Article Synopsis
- - The study examines how growth factors (GFs) and glucocorticoids (GCs) interact during cell development and disease, revealing that transcription factors like p53 and NF-κB are involved in this crosstalk.
- - GCs inhibit GFs' positive feedback while promoting inhibitory loops, and this interaction does not affect DNA methylation but can broaden the range of genes activated by GFs when demethylation occurs.
- - GFs enhance the GC receptor's binding to DNA to support gene activation, whereas GCs and GFs have opposing effects on chromatin modifications, highlighting complex regulatory mechanisms in gene expression.
