Differentiation of focal indeterminate marrow abnormalities with multiparametric MRI.

Purpose: To explore magnetic resonance imaging (MRI) parameters from intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI), multiecho Dixon imaging (ME-Dixon), and dynamic contrast-enhanced imaging (DCE) for differentiating focal indeterminate marrow abnormalities MATERIALS AND METHODS: Forty-two patients with 14 benign and 28 malignant focal marrow abnormalities were included. The following were independently analyzed by two readers: signal intensity (SI), contour, and margin on conventional MR images; SI on b-800 images (SI ), apparent diffusion coefficient (ADC), IVIM parameters (D D , and f), fat fraction (Ff), and DCE parameters (time-to-signal intensity curve pattern, iAUC, K , k , and v ). The MR characteristics and parameters from benign and malignant lesions were compared with a chi-squared test and the Mann-Whitney U-test, respectively.