Waldeyer ring microbiome in relation to chemoradiation-induced oral mucositis in patients with nasopharyngeal carcinoma.

Background: Waldeyer lymphatic ring surrounds the nasopharynx and oropharynx, and no study to date has correlated its microbiome with the severity of oral mucositis (OM) in patients with nasopharyngeal carcinoma (NPC) receiving chemoradiotherapy.

Methods: We performed 16S rRNA sequencing to characterize bacterial microbiome in tumor-affected nasopharynx and the surrounding normal oropharynx. We plotted the abundance and diversity of bacterial taxa and their phylogenetic distance and networks to visualize and compare the differences in pretreatment overall bacterial communities between the nasopharynx and oropharynx in patients with NPC with varying degrees of chemoradiotherapy-induced OM and quality of life.

Creating a Healthy Life for the Elderly through Participation in Self-Media: A Study on the Demands of the Elderly in Self-Media.

In recent years, with the trends in digital media and a shift in the sources of information, self-media has gradually become a unique new type of media with considerable potential. Numerous related studies have also indicated that participating in self-media positively impacts the elderly, especially in self-media regarding healthcare and welfare. However, research has seldom explored the demands and services for elderly participation in self-media.