Publications by authors named "Ynz Wang"

Article Synopsis
  • Pure mucosal neuroma syndrome (MNS) is a rare neurocutaneous disorder that is part of multiple endocrine neoplasia (MEN) type 2B but presents without the typical hormonal issues associated with MEN2B, instead showing distinct physical features like prominent corneal nerves.* -
  • A case study of a 41-year-old patient revealed itchy eyes, blocked eyelid glands, and a small neoplasm on the eye, with testing positive for the SOS1 mutation, indicating this patient fits the profile for MNS.* -
  • Recognizing ocular features of MNS is crucial for patients, as they may avoid unnecessary thyroid surgeries commonly suggested for MEN2B, although ongoing monitoring and genetic counseling are still recommended.*
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Vascular remodeling is an important pathological feature of hypertension, leading to increased vascular resistance and reduced compliance. Endothelial cell (EC) and vascular smooth muscle cell (VSMC) dysfunction is involved in vascular remodeling. Long noncoding RNAs are potential regulators of EC and VSMC function.

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Atherosclerosis is one of the most common vascular disorders. Endothelial cell (EC) dysfunction and vascular smooth muscle cell (VSMC) proliferation contributes to the development of atherosclerosis. Long non-coding RNAs (lncRNAs) have been implicated in several biological processes and human diseases.

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The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non-coding RNAs (lncRNAs) are important players in many biological processes and human disorders. We previously identified a role of MALAT1 in microvascular dysfunction.

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