Publications by authors named "Yizhou Du"
Article Synopsis
- T helper 2 (Th2) cells play a dual role in the body by fighting parasites and aiding tissue repair, but they can also cause problems in conditions like asthma and tissue fibrosis.
- Research showed that Th2 cells from asthma patients have increased levels of a protein called HIF2α, which is crucial for their pathogenic development.
- Targeting HIF2α could be a potential treatment strategy for asthma, as its inhibition was found to reduce harmful Th2 cell differentiation and decrease airway inflammation.
Ubiquitination is a post-translational modification mechanism which regulates a variety of signaling pathways and crucial biological processes. It has long been known that ubiquitination regulates the fundamental cellular processes through the induction of proteasomal degradation of target proteins. Meanwhile, the nondegradative types of polyubiquitination modification have been appreciated as important regulatory machinery by modulating the activity or subcellular localization of key signaling proteins.
View Article and Find Full Text PDFIntegrated omic techniques and their genomic features for invasive weeds.
Funct Integr Genomics
January 2023
Many emerging invasive weeds display rapid adaptation against different stressful environments compared to their natives. Rapid adaptation and dispersal habits helped invasive populations have strong diversity within the population compared to their natives. Advances in molecular marker techniques may lead to an in-depth understanding of the genetic diversity of invasive weeds.
View Article and Find Full Text PDFArticle Synopsis
- - Invasive plants threaten biodiversity and can lead to significant economic losses, and their impacts are likely to be intensified by climate change factors like temperature and precipitation changes.
- - A review of 176 plant species revealed that while both native and invasive plants may show improved performance when exposed to multiple global change factors, their competitiveness tends to suffer overall, giving invasive plants an edge under certain conditions.
- - The study highlights the need for more research on the combined effects of climate change on plant invasions, as predicting these invasions based solely on individual factors may not provide an accurate picture of their dynamics.
Nitrogen (N) is one of the essential nutrients for plant growth. Appropriate application of N can improve the N use efficiency (NUE) and significantly promote plants' growth. However, under N toxic conditions, the relationship between the growth and antioxidant system of invasive plants under different N forms and competitive treatments is not fully understood.
View Article and Find Full Text PDFIntroduction: It is very important to monitor the infection of as a potential threat to the sheep industry. Southern Xinjiang is a major sheep breeding base in China, however, there is no relevant information concerning the infection of the region's ovine stock with this bacteria at present. This study aimed to address this knowledge gap.
View Article and Find Full Text PDFProgesterone (P4) antagonizes estradiol (E2) in synaptic remodeling in the hippocampus during the rat estrous cycle. To further understand how P4 modulates synaptic plasticity, we used entorhinal cortex lesions, which induce E2-dependent neurite sprouting in the hippocampus. In young ovariectomized rats, the E2-dependent entorhinal cortex lesion-induced sprouting was attenuated by concurrent treatment with P4 and E2.
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