Publications by authors named "Yizhen Wang"

This experiment aimed to investigate the effects of dietary metabolizable energy (ME) and crude protein (CP) levels and their interaction on the performance, meat quality, and cecal microbiota of Taihe Silky Fowl (Gallus gallus domesticus Brisson) during the growing period. A total of 2160 55-day-old Taihe Silky Fowl (half male and half female) were randomly divided into 9 groups with 6 replicates per group and 40 chickens per replicate. The fowl were fed with a 3 × 3 factor diet (ME: 11.

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In order to elucidate the dynamic changes of quality characteristics in Xanthoceras sorbifolium leaf tea (XLT), this work investigated the chemical components, volatile profile, and antioxidant properties at key stages of fixation, shaping, and drying. The process of fixation and drying emerged as critical stages that affected the chemical components and taste of XLT. Total polyphenols, reducing sugars and chlorophyll were the differential compounds, which decreased by 29.

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  • - Oculocutaneous albinism type 2 (OCA-2) is linked to changes in the OCA2 gene, and this study aims to better classify uncertain gene variants using a method called multiplex assays of variant effect (MAVEs).
  • - By analyzing variants from publicly available data, the research found that pathogenic variants behaved abnormally while benign ones worked normally, supporting a structured re-classification process for uncertain variants.
  • - Out of 38 patients, the analysis provided a clearer diagnosis for 7 individuals, demonstrating the effectiveness of MAVEs for improving genetic testing and offering a valuable resource for future research and public clinical databases.
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Dosing iron salts is a widely adopted strategy for sewer odor and corrosion management, and it can affect bioenergy recovery during anaerobic digestion (AD) of sludge in downstream wastewater treatment plants. However, the different impacts of in-sewer iron salt dosing on AD, depending on the types of iron and digestion conditions, remain unclear. Therefore, this study investigated the impact of in-sewer ferrous (Fe(II)) and ferrate (Fe(VI)) dosing on bioenergy recovery in both conventional AD and AD with thermal hydrolysis pretreatment (THP).

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Various problems and obstacles are encountered during pig farming, especially the weaning phase when switching from liquid to solid feed. Infection by pathogenic bacteria causes damage to the intestinal barrier function of piglets, disrupts the balance of the intestinal microbiota, and destroys the chemical, mechanical, and immune barriers of the intestinal tract, which is one of the main causes of gut inflammation or gut diseases in piglets. The traditional method is to add antibiotics to piglet diets to prevent bacterial infections.

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Information on the spatiotemporal variations in the composition and sources of organic aerosols (OA) is needed to identify regional influences and to establish effective control measures. Here, 23-h PM samples were collected in five central cities of the Yangtze River Delta in eastern China, including Nanjing, Suzhou, Wuxi, Changzhou, and Zhenjiang, every three days from 2020/09/01 to 2021/02/28. Each sample was analyzed for water-soluble inorganic ions, organic carbon (OC), elemental carbon (EC), and organic molecular markers (OMMs).

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Objective: The experiment aimed to study the effect of dietary metabolizable energy (ME) and crude protein (CP) on laying performance, egg quality, serum routine biochemical and lipid metabolism indicators, the apparent digestibility of nutrients, and fecal microbiota of Taihe Silky Fowl (TSF) during the peak laying period.

Methods: A total of 540 26-week-old TSF female fowls were randomly allocated to 9 groups with 5 replicates per group and 12 fowls per replicate. The fowls were fed with a 3 × 3 factorial arrangement of treatments diets (ME:10.

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SNF1-RELATED KINASE 2 (SnRK2) plays a crucial role in plants' stress response. Although studies have reported that the overexpression of several SnRK2 family members in different plants leads to improved stress tolerance, it is difficult to elucidate the mechanisms by which SnRK2s regulate stress tolerance due to the variability of experimental variables in these studies. Therefore, we used meta-analysis to comprehensively analyze 22 parameters that can reflect drought tolerance and salinity tolerance in SnRK2s-transformed plants and to explore the effects that different experimental variables between studies have on the relevant plant parameters.

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The effects of dietary metabolizable energy (ME) and crude protein (CP) on the growth performance, meat quality, and cecal microbiota of Taihe Silky Fowl (TSF) during fattening were investigated. In total, 900 twelve-week-old female fowl were randomly allocated to 9 treatments (5 replicates per group, 20 fowl per replicate), and were fed a 3 × 3 factorial arrangement of treatments diets (ME: 11.30, 11.

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  • The nucleotide excision repair (NER) system helps protect against DNA damage, and deficiencies in this system can lead to increased mutations and cancer risks.
  • A study analyzed 19 NER gene polymorphisms in 416 Wilms tumor cases and 936 controls from East China, finding that certain XPD polymorphisms decreased Wilms tumor risk while some XPG polymorphisms increased it.
  • The research suggests that these gene variations affect nearby gene expression and emphasizes the need for further studies with larger sample sizes to validate these associations.
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Background: Neuroblastoma (NB) is a well-known pediatric malignancy intertwined with neurodevelopment. Previously implicated in neuronal differentiation, Zinc Finger Protein 536 (ZNF536) has emerged as a promising prognostic and immune-related biomarker in our pan-cancer analysis.

Methods: Single-cell RNA transcriptome sequencing, bulk transcriptome analysis, and immuno-histochemistry were used to assess ZNF536 expression and its association with prognosis.

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  • Contaminant-bearing polystyrene microplastics (PSMPs) significantly differ in toxicity compared to contaminant-free ones, specifically affecting how they absorb contaminants like chromium (Cr).
  • Research shows that Cr-loaded aged PSMPs cause severe health issues in mice, including weight loss, oxidative stress, inflammation, and intestinal damage.
  • The study identifies the mechanisms behind these effects, indicating that PSMPs@Cr lead to increased oxidative stress and inflammation through specific cellular pathways, highlighting their potential as hazardous materials contributing to intestinal diseases.
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  • "Zaojiaomi" is a traditional food derived from the endosperm of specific plant species, but there's limited study on Gymnocladus chinensis endosperm.
  • A research study used a metabolomics approach to analyze and compare the metabolites in Gymnocladus chinensis, Gleditsia sinensis, and Gleditsia japonica endosperms, identifying a significant number of different metabolites.
  • The findings suggest that Gymnocladus chinensis has unique compounds that could enhance antioxidant activity and is rich in beneficial nutrients like L-arginine and zinc, highlighting its potential as a functional food.
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The Jiangshan black pig is an indigenous pig breed in China, renowned for its superior meat quality and adaptability to roughage. However, the population of Jiangshan black pigs has dwindled due to the introduction of cosmopolitan pig breeds and the outbreak of African swine fever, putting them at risk of extinction. To offer insights into the conservation and breeding of Jiangshan black pigs, this study involved 118 Jiangshan black pigs as the research subjects and employed the Zhongxin-1 Porcine Breeding Array PLUS chip to detect whole-genome SNPs.

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Population-wide increase in life expectancy is a source of aggregate longevity risk. Life insurance is a natural instrument to manage the risk. Previous studies used chronological age to examine the relationship between aging and life insurance purchase, which ignored the impact of subjective life expectancy-the real perception of remaining time.

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The petal blight disease of alpine Rhododendron severely impacts the ornamental and economic values of Rhododendron. Plant secondary metabolites play a crucial role in resisting pathogenic fungi, yet research on metabolites in alpine Rhododendron petals that confer resistance to pathogenic fungi is limited. In the present study, the secondary metabolites in , , and petals with anti-pathogenic activity were screened through disease index analysis, metabolomic detection, the mycelial growth rate, and metabolite spraying experiments.

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Background: Neuroblastoma, a pediatric malignancy, is significantly influenced by genetic factors. Prior research indicates that the rs1052133 G > C polymorphism correlates with a decreased risk of neuroblastoma.

Methods: We analyzed 57 neuroblastoma and 21 adrenal samples, using immunohistochemistry to measure OGG1 and STUB1 expression levels.

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Achieving chemical accuracy in describing reactions involving both main-group elements and transition metals poses a substantial challenge for density functional approximations (DFAs), primarily due to the significantly different behaviors for electrons moving in the s,p-orbitals or in the d,f-orbitals. MOR41, a representative dataset of transition metal chemistry, has highlighted the PWPB95-D3(BJ) functional, a B2PLYP-type doubly hybrid (bDH) approximation equipped with an empirical dispersion correction, as the leading functional thus far (Dohm et al., J Chem Theory Comput 2018;14: 2596-2608).

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Accurate description of the static correlation poses a persistent challenge in electronic structure theory, particularly when it has to be concurrently considered with the dynamic correlation. We develop here a method in the generalized Kohn-Sham density functional theory (DFT) framework, named R-xDH7-SCC15, which achieves an unprecedented accuracy in capturing the static correlation, while maintaining a good description of the dynamic correlation on par with the state-of-the-art DFT and wave function theory methods, all grounded in the same single-reference black-box methodology. Central to R-xDH7-SCC15 is a general-purpose static correlation correction (SCC) model applied to the renormalized XYG3-type doubly hybrid method (R-xDH7).

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  • * A total of 2,386 English-language papers were included, with the United States leading in publications at over 31%, and the Chinese Academy of Sciences identified as the top institution in this field.
  • * The research highlights notable authors, such as Omid C. Farokhzad, who has the highest citation count, and identifies "gold nanoparticles" as a recent trending topic, providing insights for future researchers on important publications and emerging research areas.
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