Background: Insulin resistance (IR) is an independent predictor of atrial fibrillation (AF), but the specific utility of the triglyceride-glucose (TyG) index as a predictive marker for the incidence of AF in the acute coronary syndrome (ACS) population has not yet been explored.
Objective: To explore the correlation between TyG index and the risk of AF in ACS patients and to establish a predictive model.
Methods: A retrospective study was conducted on 613 ACS patients admitted to the Department of Cardiovascular Medicine at the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine from January 2022 to September 2024.
The hypothalamus plays a fundamental role in controlling lipid metabolism through neuroendocrine signals. However, there are currently no available drug targets in the hypothalamus that can effectively improve human lipid metabolism. In this study, we found that the antimalarial drug artemether (ART) significantly improved lipid metabolism by specifically inhibiting microglial activation in the hypothalamus of high-fat diet-induced mice.
View Article and Find Full Text PDFSensitive, intelligent point-of-care test (iPOCT) methods for small molecules like aflatoxin B1 (AFB1) are urgently needed for food and the environment. The challenge remains of surface control in iPOCT. Herein, we developed an electrochemical sensor based on the DNA pyramid (DNP), combining a smartphone, app, and mobile electrochemical workstations to detect AFB1.
View Article and Find Full Text PDFEffective tuning of carrier dynamics in two-dimensional (2D) materials is significant for multi-scene device applications. Using first-principles and nonadiabatic molecular dynamics calculations, the kinetics of O, HO, and N intercalation into 2D WSe/WS van der Waals heterostructures and its effect on carrier dynamics have been comprehensively explored. It is found that the O molecule prefers to dissociate into atomic O atoms spontaneously after intercalation of WSe/WS heterostructures, whereas HO and N molecules remain intact.
View Article and Find Full Text PDFEdges are important, because they dictate the stability and properties of nanoribbons. Here, we reveal a universal reconstruction of the ZZ edge into a (2 × 1) tubed [ZZ(Tube)] edge, enabling an ultimate narrow nanotube to terminate nanoribbons for α-puckered group-V elemental and compound monolayers (GeS/Se and SnS/Se). The reconstructed edge formations are confirmed by CALYPSO.
View Article and Find Full Text PDFSensitive and point-of-care detection of small toxic molecules plays a key role in food safety. Aflatoxin, a typical small toxic molecule, can cause serious healthcare and economic issues, thereby promoting the development of sensitive and point-of-care detection. Although ELISA is one of the official detection methods, it cannot fill the gap between sensitivity and point-of-care application because it requires a large-scale microplate reader.
View Article and Find Full Text PDFTwo-dimensional (2D) semiconductors with suitable direct band gaps, high carrier mobility, and excellent open-air stability are especially desirable for material applications. Herein, we show theoretical evidence of a new phase of a copper(i) sulfide (CuS) monolayer, denoted δ-CuS, with both novel electronic properties and superior oxidation resistance. We find that both monolayer and bilayer δ-CuS have much lower formation energy than the known β-CuS phase.
View Article and Find Full Text PDFAmong various two-dimensional (2D) materials, monolayer group-III monochalcogenides (GaS, GaSe, InS, and InSe) stand out owing to their potential applications in microelectronics and optoelectronics. Devices made of these novel 2D materials are sensitive to environmental gases, especially O molecules. To address this critical issue, here we systematically investigate the oxidization behaviors of perfect and defective group-III monochalcogenide monolayers by first-principles calculations.
View Article and Find Full Text PDFRidged, orthorhombic two-dimensional (2D) group-V elemental and group IV-VI compound analogues of phosphorene provide a versatile platform for nanoelectronics, optoelectronics, and clean energy. However, phosphorene is vulnerable to oxygen in ambient air, which is a major obstacle for its applications. Regarding this issue, here we explore the oxidation behavior of monolayer group-IV monochalcogenides (GeS, GeSe, SnS, and SnSe), in comparison to that of phosphorene and arsenene by first-principles calculations.
View Article and Find Full Text PDFCadmium (Cd) in 8698 peanut samples collected from China in 2009-2014 was studied to evaluate its contamination level, distribution, and health risk. The average Cd concentration was 0.1684 mg kg; the range of 2.
View Article and Find Full Text PDFGraphene oxide was fabricated by a simple method and applied to magnetic solid-phase extraction. In a pretreatment procedure before the sesamol, sesamin and sesamolin in sesame oil were detected by high performance liquid chromatography. Several parameters affecting the extraction efficiency were investigated, including the type and volume of desorption solvent, desorption time and the amount of sorbent.
View Article and Find Full Text PDFBased on the 2983 peanut samples from 122 counties in six provinces of China's Yangtze River ecological region collected between 2009-2014, along with the dietary consumption data in Chinese resident nutrition and health survey reports from 2002 and 2004, dietary aflatoxin exposure and percentiles in the corresponding statistics were calculated by non-parametric probability assessment, Monte Carlo simulation and bootstrap sampling methods. Average climatic conditions in the Yangtze River ecological region were calculated based on the data from 118 weather stations via the Thiessen polygon method. The survey results found that the aflatoxin contamination of peanuts was significantly high in 2013.
View Article and Find Full Text PDFJ Phys Condens Matter
August 2010
Using first-principles calculations, the structural, mechanical and electronic properties of the experimentally synthesized B(12)-based ternary crystals (AlMgB(14), AlNaB(14), AlLiB(14), Mg(2)B(14), MgSi(2)B(12), MgC(2)B(12), Li(2)Si(2)B(12) and Li(2)C(2)B(12)) have been investigated. The theoretical equilibrium lattice constants of these crystals agree with the experimental values. The Vickers hardness (H(v)) estimated from the theoretical Young's moduli ranges from 20 to 30 GPa, and the MgC(2)B(12) compound (H(v) = 31.
View Article and Find Full Text PDFYing Yong Sheng Tai Xue Bao
October 2009
Flaveria bidentis (Asteraceae), a potential exotic invasive weed to agro-ecosystem and rangeland ecosystem, has recently invaded Tianjin City and Hebei Province (Hengshui and Langfang) in North China, and is spreading further. Based on its current geographical distribution in the world, the potential distribution areas of this weed in China were predicted by using CLIMEX software, aimed to assess the potential risks of this invasive weed. Following provinces in China could be the potential areas being invaded by F.
View Article and Find Full Text PDF