Publications by authors named "Yiyun Chiang"
Article Synopsis
- Heart failure (HF) is becoming more common and is linked to high risks, especially in obese individuals; this study explores how fluctuations in body mass index (BMI) can affect HF risk.
- Researchers analyzed data from over 99,000 participants in the UK Biobank, focusing on those with multiple BMI measurements over several years and excluding those already diagnosed with heart failure or cancer.
- The findings indicate that greater variability in BMI over time is significantly associated with an increased risk of developing heart failure, suggesting that tracking BMI fluctuations may be important for predicting HF incidence.
Article Synopsis
- A January 2023 safety concern was raised by the CDC and FDA regarding the risk of ischemic stroke in adults aged 65 and older receiving the Pfizer-BioNTech COVID-19 bivalent vaccine.
- The study aimed to assess stroke risk related to the COVID-19 bivalent vaccine, both alone and when administered with a high-dose or adjuvanted influenza vaccine.
- Analysis of 11,001 Medicare beneficiaries who had strokes post-vaccination found no significant associations between the bivalent COVID-19 vaccine and different types of stroke within specific time frames.
Article Synopsis
- Heart failure (HF) is a serious and increasingly common condition linked to high mortality and morbidity, with obesity recognized as a significant risk factor.* -
- A study analyzed data from 99,368 middle-aged white participants, assessing the impact of fluctuations in body mass index (BMI) over time on the risk of developing HF.* -
- Results indicated that greater variability in BMI is associated with a higher risk of incident heart failure, suggesting that tracking long-term BMI changes could improve cardiovascular risk predictions.*
Genome-wide association studies (GWAS) of circulating metabolites have revealed the role of genetic regulation on the human metabolome. Most previous investigations focused on European ancestry, and few studies have been conducted among populations of African descent living in Africa, where the infectious disease burden is high (e.g.
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