Microvascular invasion is associated with poor prognosis in renal cell carcinoma: a retrospective cohort study and meta-analysis.

Background: This retrospective cohort study and meta-analysis aims to explore the association between microvascular invasion (MVI) and clinicopathologiccal features, as well as survival outcomes of patients with renal cell carcinoma (RCC).

Material And Methods: The retrospective cohort study included 30 RCC patients with positive MVI and another 75 patients with negative MVI as controls. Clinicopathological features and follow-up data were compiled.

Clinical trial: seven-day vonoprazan- versus 14-day proton pump inhibitor-based triple therapy for first-line Helicobacter pylori eradication.

Background: One-week triple therapy with vonoprazan is endorsed by Japanese guidelines as an alternative to proton pump inhibitor (PPI)-based triple therapy for first-line Helicobacter pylori eradication. This contrasts with Western guidelines recommending 2-week PPI-based triple therapy.

Aim: To verify the non-inferiority of 1-week vonoprazan-based triple therapy versus 2-week PPI-based triple therapy as first-line H.

Metal-Free -Formylation of Amines with CO and Hydrosilane by Nitrogen-Doped Graphene Nanosheets.

-Formylation of amines with carbon dioxide (CO) as a carbonyl source is emerging as an important way for CO transformation into high-value-added chemicals; however, the developed catalytic systems mainly focused on transition-metal-based homogeneous catalysts. Herein, we reported rationally designed nitrogen-doped graphene nanosheets (NG) as metal-free catalysts for -formylation of various amines with CO and hydrosilane to formamide under mild conditions. The NG catalyst displayed a wide amine scope with the desired formamide yields up to >99%, demonstrating its comparable catalytic performance to the reported transition-metal-based catalysts.