Publications by authors named "Yiyu Xiang"

Amaryllidaceae alkaloids (AAs) are complex plant secondary metabolites possessing a wide range of biological activities. 4'-O-methylnorbelladine (4OMN) is the branchpoint intermediate for the entire AAs, and was the last common intermediate before AA pathway branches diverge. The cyclization of 4OMN by C-C oxidative coupling, which can afford ', ', and ' scaffold, was catalyzed by cytochrome P450 96T (CYP96T) family enzymes.

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Article Synopsis
  • Cinnamyl alcohol dehydrogenase (CAD) is important for lignin biosynthesis, and researchers identified 10 CAD genes in tobacco, emphasizing limited prior knowledge about this gene family in the plant.
  • The study found that the tobacco CADs displayed high sequence similarity and conserved binding motifs, with NtCAD1 and NtCAD2 showing strong connections to the lignin production process.
  • Functional analysis revealed that NtCAD1-1 and NtCAD1-2 are key players in lignin synthesis, while NtCAD2 responds mainly to stress conditions, suggesting distinct but overlapping roles for these CAD genes in tobacco.
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Synthetic biology aims to engineer and redesign biological systems for useful real-world applications in biomanufacturing, biosensing and biotherapy following a typical design-build-test cycle. Inspired from computer science and electronics, synthetic gene circuits have been designed to exhibit control over the flow of information in biological systems. Two types are Boolean logic inspired TRUE or FALSE digital logic and graded analog computation.

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Efficiency of yeast transformation is determined by the rate of yeast endocytosis. The aim of this study was to investigate the effect of introducing amino acids and other nutrients (inositol, adenine, or p-aminobenzoic acid) in the transformation medium to develop a highly efficient yeast transformation protocol. The target of rapamycin complex 1 (TORC1) kinase signalling complex influences the rate of yeast endocytosis.

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