Urinary Proteomics for Noninvasive Prenatal Screening of Trisomy 21: New Biomarker Candidates.

Trisomy 21 is a common birth defect in humans. Screening for trisomy 21 is one of the most important tasks in routine prenatal care and robust noninvasive diagnostics are needed in clinical practice. Urinary proteomics offers a new research platform for diagnostics innovation in this context.