Publications by authors named "Yiyi Lan"
Diagnostic value of nanopore sequencing of cerebrospinal fluid samples in tuberculous meningitis.
Diagn Microbiol Infect Dis
February 2025
Article Synopsis
- - The study aimed to evaluate how effective nanopore sequencing technology is for diagnosing tuberculous meningitis (TBM) using cerebrospinal fluid samples from patients.
- - Compared to traditional methods like acid-fast staining and culture, nanopore sequencing had a sensitivity of 43.30% and an area under the ROC curve of 0.661, indicating better performance overall.
- - When nanopore sequencing was used alongside imaging techniques, it achieved the best diagnostic results with increased sensitivity, specificity, and predictive values, showing its potential as a reliable tool for TBM diagnosis.