Development of a PMGDNI model to predict the probability of three-month unfavorable outcome acute ischemic stroke after endovascular treatment: a cohort study.

Background: Patients with acute large vessel occlusion stroke (ALVOS) may exhibit considerable variability in clinical outcomes following mechanical thrombectomy (MT). This study aimed to develop a novel statistical model predicting functional independence three months post-endovascular treatment for acute stroke and validate its performance within the cohort.

Method: Consecutive patients undergoing endovascular treatment for acute stroke with large vessel occlusion were randomly divided into a modeling group and a validation group in a 7:3 ratio.

Co O Quantum Dots Intercalation Liquid-Crystal Ordered-Layered-Structure Optimizing the Performance of 3D-Printing Micro-Supercapacitors.

The effects of near surface or surface mechanisms on electrochemical performance (lower specific capacitance density) hinders the development of 3D printed micro supercapacitors (MSCs). The reasonable internal structural characteristics of printed electrodes and the appropriate intercalation material can effectively compensate for the effects of surface or near-surface mechanisms. In this study, a layered structure is constructed inside an electrode using an ink with liquid-crystal characteristics, and the pore structure and oxidation active sites of the layered electrode are optimized by controlling the amount of Co O -quantum dots (Co O QDs).

Ethanol-Induced Ni -Intercalated Cobalt Organic Frameworks on Vanadium Pentoxide for Synergistically Enhancing the Performance of 3D-Printed Micro-Supercapacitors.

The synthesis of metal-organic framework (MOF) nanocomposites with high energy density and excellent mechanical strength is limited by the degree of lattice matching and crystal surface structure. In this study, dodecahedral ZIF-67 is synthesized uniformly on vanadium pentoxide nanowires. The influence of the coordination mode on the surface of ZIF-67 in ethanol is also investigated.

Potential treatment with Chinese and Western medicine targeting NSP14 of SARS-CoV-2.

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a serious global health threat. This raises an urgent need for the development of effective drugs against the deadly disease. SARS-CoV-2 non-structural protein 14 (NSP14) carrying RNA cap guanine N7-methyltransferase and 3'-5' exoribonuclease activities could be a potential drug target for intervention.

Replication of hepatitis E virus in the ovary and promotion of oocyte apoptosis in rabbits infected with HEV-4.

Hepatitis E virus (HEV) infection can induce infertility and miscarriage in pregnant women and infect neonates through vertical transmission. However, the mechanism of infertility and vertical transmission remains unclear. In the present study, we evaluated the replication of HEV in the ovary and structural and molecular changes induced by HEV after intraperitoneal injection of HEV in rabbits.

Fabrication of antireflective sub-wavelength structures on silicon nitride using nano cluster mask for solar cell application.

We have developed a simple and scalable approach for fabricating sub-wavelength structures (SWS) on silicon nitride by means of self-assembled nickel nanoparticle masks and inductively coupled plasma (ICP) ion etching. Silicon nitride SWS surfaces with diameter of 160-200 nm and a height of 140-150 nm were obtained. A low reflectivity below 1% was observed over wavelength from 590 to 680 nm.