Plants encounter various abiotic stresses throughout growth and development, with aluminum stress emerging as a major global agricultural challenge that hinders plant growth and limits crop yields in acidic soils. In this study, nanomaterials with dual functions, controlled release and adsorption, were constructed to alleviate aluminum toxicity. Specifically, two metal-organic frameworks, UiO-66 and ZIF-8, were used to load naphthylacetic acid and tryptophan, respectively.
View Article and Find Full Text PDFThis paper presents an improved gas sensor based on the dual-excitation of quartz-enhanced photothermal spectroscopy (QEPTS) using a single quartz tuning fork (QTF) for signal detection. The silver coating on one side of the QTF was chemically etched to increase the laser power interacted with QTF for QEPTS signal excitation. By etching the silver coating on one side of QTF, the reflection structure between the silver coating of the other side of QTF and the external flat mirror was established.
View Article and Find Full Text PDFRetraction of 'PEG-poly(amino acid)s/EpCAM aptamer multifunctional nanoparticles arrest the growth and metastasis of colorectal cancer' by Yingru Zhang , , 2021, , 3705-3717, https://doi.org/10.1039/D1BM00160D.
View Article and Find Full Text PDFThe own-race bias (ORB) is an effect in which humans remember faces from their own race better than faces from another race. Where people look when processing faces of different races plays a role in this effect, but the exact relationship between looking and the ORB is debated. One perspective is that the same facial features are important for memory for faces of all races and the ORB emerges when people look longer at the useful features for own- than other-race faces.
View Article and Find Full Text PDFBackground: Urine sediment examination is a time-tested and non-invasive diagnostic tool. This study investigated the characteristics of urine sediment and its association with severity and renal outcomes in diabetic nephropathy (DN) patients.
Methods: A total of 201 biopsy-proven diabetic nephropathy patients (according to the pathological classification of diabetic nephropathy proposed by the Renal Pathology Society in 2010) who underwent manual urine sediment microscopic examination were included.
This study aimed to explore naringin's potential to promote the osteogenic differentiation of MC3T3-E1 under oxidative stress. It delved into Nar's connection with the Wnt/β-catenin and PI3K/Akt signaling pathways. Initially, 2911 OP-related genes were analyzed, revealing close ties with the PI3K/Akt and Wnt pathways alongside oxidative stress.
View Article and Find Full Text PDFBackground: Blepharoptosis is a common symptom in ophthalmology clinic, but eyelid retraction when smiling in a ptosis eye is a rare manifestation. Here we report a novel manifestation that eyelid retraction during smiling in a patient with monocular congenital ptosis.
Case Description: A 10-year-old girl with isolated and mild unilateral congenital ptosis showed eyelid retraction in ptotsis eye when smiling together with a lid lag on downgaze.
Human health and the ecological balance are both gravely threatened by heavy metal pollution brought on by global industrialization. Probiotics are thought to represent a novel class of medicinal products for reducing heavy metal toxicity. Though simultaneous poisoning of numerous heavy metals is more prevalent, the majority of current studies on probiotics in the treatment of heavy metal poisoning concentrate on a single heavy metal.
View Article and Find Full Text PDFDiabetic wounds remain a global challenge due to disordered wound healing led by inflammation, infection, oxidative stress, and delayed proliferation. Therefore, an ideal wound dressing for diabetic wounds not only needs tissue adhesiveness, injectability, and self-healing properties but also needs a full regulation of the microenvironment. In this work, adhesive wound dressings (HA-DA/PRP) with injectability were fabricated by combining platelet rich plasma (PRP) and dopamine-modified-hyaluronic acid (HA-DA).
View Article and Find Full Text PDFIntroduction: A previous study showed that the renal risk score (RRS) was transferrable to antiglomerular basement membrane (anti-GBM) disease and proposed a risk stratification according to the need of renal replacement therapy (RRT) and the percentage of normal glomeruli (N). Herein, we analyzed the risk factors associated with kidney outcomes in patients with biopsy-proven anti-GBM disease and evaluated these 2 prognosis systems.
Methods: A total of 120 patients with biopsy-proven anti-GBM disease with complete clinicopathologic and outcome data were analyzed.
Plants trigger a robust immune response by activating massive transcriptome reprogramming through crosstalk between PTI and ETI. However, how PTI and ETI contribute to the quantitative or/and qualitative output of immunity and how they work together when both are being activated were unclear. In this study, we performed a comprehensive overview of pathogen-triggered transcriptomic reprogramming by analyzing temporal changes in the transcriptome up to 144 h after Colletotrichum gloeosporioides inoculated in Populus.
View Article and Find Full Text PDFGlobal emission reductions still must address winter fine particulate matter (PM) pollution in urban basins with enclosed terrains and frequent cold air pool (CAP) events when the temperatures within the basin are colder than above it. The effects of urban basin aerosol-boundary layer interactions on PM pollution during CAP events remain unclear. Intensive boundary layer observations in January 2021 and numerical models were used to investigate this issue in the semi-arid urban Lanzhou Basin of China.
View Article and Find Full Text PDFIntroduction: This study investigated the impact of different modes of physical exercise on the emotional and cognitive levels of patients with Substance Use Disorder (SUD). By exploring the most effective intervention types, cycle, frequency, and duration, we aimed to provide evidence-based recommendations for the adjunctive treatment of SUD.
Methods: We conducted a systematic search in five databases, including PubMed, Web of Science, The Cochrane Library, ScienceDirect, and EBSCO, from database inception up to May 2023, and identified 4,255 randomized controlled trials addressing the influence of physical exercise on the emotional and cognitive levels of SUD patients.
The 2D echocardiography semantic automatic segmentation technique is important in clinical applications for cardiac function assessment and diagnosis of cardiac diseases. However, automatic segmentation of 2D echocardiograms also faces the problems of loss of image boundary information, loss of image localization information, and limitations in data acquisition and annotation. To address these issues, this paper proposes a semi-supervised echocardiography segmentation method.
View Article and Find Full Text PDFComb Chem High Throughput Screen
January 2024
Introduction: Traditional Chinese medicine (TCM) can modulate the immune function of tumor patients in various ways. Zuojin Wan (ZJW, a 6:1 ratio of Huanglian and Wuzhuyu) can modulate the microenvironment of ulcerative colitis, but its role in regulating the CRC microenvironment remains unclear. Exploring the role of ZJW in CRC immunomodulation may improve the antitumor effect of existing immunotherapeutic strategies.
View Article and Find Full Text PDFThe high prevalence of depressive disorders in individuals with cancer and their contribution to tumour progression is a topic that is gradually gaining attention. Recent evidence has shown that there are prominent connections between immune gene variants and mood disorders. The homeostasis of the tumour immune microenvironment (TIME) and the infiltration and activation of immune cells play a very important role in the antitumour effect.
View Article and Find Full Text PDFComput Biol Med
January 2024
In the current era, diffusion models have emerged as a groundbreaking force in the realm of medical image segmentation. Against this backdrop, we introduce the Diffusion Text-Attention Network (DTAN), a pioneering segmentation framework that amalgamates the principles of text attention with diffusion models to enhance the precision and integrity of medical image segmentation. Our proposed DTAN architecture is designed to steer the segmentation process towards areas of interest by leveraging a text attention mechanism.
View Article and Find Full Text PDFIn recent years, air emergency rescue capabilities have become increasingly important as an indicator of national comprehensive strength and development status. Air emergency rescue performs an indispensable role in addressing social emergencies by virtue of its fast response capabilities and extensive coverage. This vital aspect of emergency response ensures the timely deployment of rescue personnel and resources, enabling efficient operations in diverse and often challenging environments.
View Article and Find Full Text PDFJ Diabetes Complications
August 2023
Aims: In diabetic kidney disease (DKD) patients, early-onset T2DM effects on renal disease severity and outcomes remain uncertain. Herein, we aim to investigate the clinicopathological characteristics and renal outcomes in DKD patients with early-onset T2DM.
Methods: 489 patients with T2DM and DKD were retrospectively recruited and classified as having early (age at onset of T2DM < 40 years) and late (age at onset of T2DM ≥ 40 years) T2DM onset, analyzing the clinical and histopathological data.
Herein, well-defined hollow CuS microspheres assembled from nanosheets were successfully synthesized through a facile solvothermal method. Hollow CuS microspheres have an average diameter of 1.5 μm; moreover, the primary CuS nanosheets have an ultrathin thickness of about 10 nm and are bound by {0001} polar facets.
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