Ischemic stroke (IS) is one of the top risk factors for death and disability. Meteorological conditions have an effect on IS attack. In this study, we try to develop models of medical meteorological forecast for IS attack based on machine learning and deep learning algorithms.
View Article and Find Full Text PDFSnakebite envenoming is a public health issue linked to high mortality and morbidity rates worldwide. Although antivenom has been the mainstay treatment for envenomed victims receiving medical care, the diverse therapeutic efficacy of the produced antivenom is a major limitation. is a venomous snake that poses significant concern of risks to human life in Taiwan, and successful production of antivenom against envenoming remains a considerable challenge.
View Article and Find Full Text PDFObjective: Chronic obstructive pulmonary disease (COPD) is a complicated multi-factor, multi-gene disease. Here, we aimed to assess the association of genetic polymorphisms in LINC01414/ LINC00824 and interactions with COPD susceptibility.
Methods: Three single nucleotide polymorphisms (SNPs) in LINC01414/LINC00824 was genotyped by Agena MassARRAY platform among 315 COPD patients and 314 controls.
Chronic obstructive pulmonary disease (COPD) is a high incidence in the elderly and significantly affects the quality of life. and play an important role in tobacco-related diseases and inflammatory reactions. Thus, we aim to investigate the association between / polymorphisms and the risk of COPD.
View Article and Find Full Text PDFPurpose: Genetic polymorphisms act a crucial role in chronic obstructive pulmonary disease (COPD) progression. This study aimed to investigate the correlation between CYP3A4 variants and COPD risk.
Methods: We carried out a case-control study of 821 individuals (313 patients and 508 healthy subjects) to identify the correlation of CYP3A4 SNPs with COPD risk in the Hainan Han population.
Background: Chronic obstructive pulmonary disease (COPD) is a complex pulmonary disease. Cytochrome P450 family 4 subfamily F member 2 (CYP4F2) belongs to cytochrome P450 superfamily of enzymes responsible for metabolism, its single nucleotide polymorphisms (SNPs) were reported to be involved in metabolism in the development of many diseases. The study aimed to assess the relation between CYP4F2 SNPs and COPD risk in the Hainan Han population.
View Article and Find Full Text PDFArch Bronconeumol (Engl Ed)
November 2020
Introduction: Cytochrome P450 (CYP) 2J2 is a major enzyme that controls epoxyeicosatrienoic acids biosynthesis, which may play a role in chronic obstructive pulmonary disease (COPD) development. In this study, we aimed to assess the influence of CYP2J2 polymorphisms with COPD susceptibility.
Material And Methods: A case-control study enrolled 313 COPD cases and 508 controls was to investigate the association between CYP2J2 polymorphisms and COPD risk.
Int J Chron Obstruct Pulmon Dis
April 2020
Introduction: Chronic obstructive pulmonary disease (COPD) is a lung disease closely related to exposure to exogenous substances. can activate many exogenous substances, which in turn affect lung cells. The aim of this study was to assess the association of single-nucleotide polymorphisms (SNPs) in with COPD risk in a Chinese Han population.
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