Comp Biochem Physiol C Toxicol Pharmacol
December 2024
Cathelicidin is a family of antimicrobial peptides in vertebrates that plays an important role in resistance and immunization against pathogenic microorganisms. In the present study, the full-length cDNA sequences of four novel cathelicidins (cathelicidin-1 to cathelicidin-4) in the tiger frog Hoplobatrachus rugulosus, encoding 153, 188, 132, and 160 amino acids, respectively, were firstly cloned by rapid amplification of the cDNA ends (RACE) technique. Sequence comparison and phylogenetic tree analysis indicated that the structures of the four cathelicidins are highly diverse.
View Article and Find Full Text PDFBackground: Probiotics, which are beneficial to the host, have been shown to benefit the health of cats. Lactic acid bacteria (LAB) are commonly used probiotics, but most strains used for cats are not derived from cats, leading to reduced efficacy and poor adaptation to cats. The objective was to identify LAB with promising probiotic potential specific to cats.
View Article and Find Full Text PDFA new species of the megaspiline genus Conostigmus Dahlbom with a distinct facial sulcus is described and figured from material collected in yellow pan traps. Conostigmus nankunensis Qian and Wang sp. nov.
View Article and Find Full Text PDFBackground: Heat stress significantly impacts dairy cows, primarily through oxidative stress, which undermines their health. The problem is exacerbated by the ongoing global warming trend. Lactic acid bacteria (LAB) are safe, economical, and readily accessible options for enhancing the host's antioxidant defenses and preventing oxidative damage.
View Article and Find Full Text PDFPurpose: To examine how coping style mediates the relationship between risk perception of diabetic complications and self-management, so as to provide evidence for improving the self-management level of patients with type 2 diabetes.
Patients And Methods: We recruited patients with type 2 diabetes mellitus and conducted a cross-sectional survey using a general information questionnaire, the risk perception survey-diabetes mellitus (RPS-DM), the medical coping modes questionnaire (MCMQ), and the summary of Diabetes Self-Care Activities (SDSCA). Descriptive analysis and Pearson correlation analysis were carried out with SPSS 25.
Background: is a Gram-negative, rod-shaped bacterium widely found in natural environments. It is known for causing a range of severe illnesses in mammals, particularly urinary tract infections (UTIs). This study evaluates the therapeutic efficacy of phage P2-71 against and environments.
View Article and Find Full Text PDFThere are only eight approved small molecule antiviral drugs for treating COVID-19. Among them, four are nucleotide analogues (remdesivir, JT001, molnupiravir, and azvudine), while the other four are protease inhibitors (nirmatrelvir, ensitrelvir, leritrelvir, and simnotrelvir-ritonavir). Antiviral resistance, unfavourable drug‒drug interaction, and toxicity have been reported in previous studies.
View Article and Find Full Text PDFPlant Extracts (PE) are natural substances extracted from plants, rich in various bioactive components. Exploring the molecular mechanisms and interactions involved in the vascular protective effects of PE is beneficial for the development of further strategies to protect aging blood vessels. For this review, the content was obtained from scientific databases such as PubMed, China National Knowledge Infrastructure (CNKI), and Google Scholar up to July 2024, using the search terms "Plant extracts", "oxidative stress", "vascular aging", "endothelial dysfunction", "ROS", and "inflammation".
View Article and Find Full Text PDFTheretra japonica is an important pollinator and agricultural pest in the family Sphingidae with a wide range of host plants. High-quality genomic resources facilitate investigations into behavioral ecology, morphological and physiological adaptations, and the evolution of genomic architecture. However, chromosome-level genome of T.
View Article and Find Full Text PDFIn Hymenoptera, the monophyly of Evaniomorpha has been the focus of debate among different scholars. In this study, we sequenced two mitochondrial genomes of (Hymenoptera: Megaspilidae) to analyze the mitochondrial genomic features of and provide new molecular data for phylogenetic studies of Evaniomorpha. The mitogenome sizes of and were 15,445 bp and 15,373 bp, respectively, with the of missing.
View Article and Find Full Text PDFIntroduction: The risk of ketosis is assessed by monitoring changes in plasma metabolites and cow behavior during the peripartum period. However, little is known about changes in the fecal bile acid and microbiota of cows before parturition. Therefore, this study clarified the bile acid profile and screened potential warning biomarkers in heifers 7 days before calving.
View Article and Find Full Text PDFAs an important forestry pest, Coronaproctus castanopsis (Monophlebidae) has caused serious damage to the globally valuable Gutianshan ecosystem, China. In this study, we assembled the first chromosome-level genome of the female specimen of C. castanopsis by merging BGI reads, HiFi long reads and Hi-C data.
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