NSUN6-mediated 5-methylcytosine modification of NDRG1 mRNA promotes radioresistance in cervical cancer.

Background: Radioresistance is the leading cause of death in advanced cervical cancer (CC). Dysregulation of RNA modification has recently emerged as a regulatory mechanism in radiation and drug resistance. We aimed to explore the biological function and clinical significance of 5-methylcytosine (mC) in cervical cancer radiosensitivity.

Identification of a stable major-effect quantitative trait locus for pre-harvest sprouting in common wheat (Triticum aestivum L.) via high-density SNP-based genotyping.

A major and stable QTL cQSGR.sau.3D, which can explain 33.

QTL Mapping and Validation for Kernel Area and Circumference in Common Wheat High-Density SNP-Based Genotyping.

As an important component, 1,000 kernel weight (TKW) plays a significant role in the formation of yield traits of wheat. Kernel size is significantly positively correlated to TKW. Although numerous loci for kernel size in wheat have been reported, our knowledge on loci for kernel area (KA) and kernel circumference (KC) remains limited.

Identifying optimized on-the-ground priority areas for species conservation in a global biodiversity hotspot.

Threatened species are inadequately represented within protected areas (PAs) across the globe. Species conservation planning may be improved by using public species-occurrence databases, but empirical evidence is limited of how that may be accomplished at local scales. We used the Three Parallel Rivers Region of China as a case to investigate the utility of public species data in improvement in conservation planning.

Spatial relationship between climatic diversity and biodiversity conservation value.

Capturing the full range of climatic diversity in a reserve network is expected to improve the resilience of biodiversity to climate change. Therefore, a study on systematic conservation planning for climatic diversity that explicitly or implicitly hypothesizes that regions with higher climatic diversity support greater biodiversity is needed. However, little is known about the extent and generality of this hypothesis.