Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report.

Background: Recurrent Non-Tuberculous Mycobacterial Pulmonary Disease (NTM-PD) related to treatment with Secukinumab has not been previously documented.

Case Presentation: Despite adherence to treatment and avoiding hot springs, a plaque psoriasis patient experienced persistent NTM-PD relapses.

Conclusions: There is potential association between Secukinumab, an IL-17A inhibitor, and NTM disease, echoing anti-TNF biologics' NTM risk, indicating the urgent need for further research on pathogenic mechanisms and risk factors.

HirMTL: Hierarchical Multi-Task Learning for dense scene understanding.

In the realm of artificial intelligence, simultaneous multi-task learning is crucial, particularly for dense scene understanding. To address this, we introduce HirMTL, a novel hierarchical multi-task learning framework designed to enhance dense scene analysis. HirMTL is adept at facilitating interaction at the scale level, ensuring task-adaptive multi-scale feature fusion, and fostering task-level feature interchange.

Direct oral anticoagulants in the treatment of chronic thromboembolic pulmonary hypertension patients: A retrospective cohort study.

Introduction: Direct oral anticoagulants (DOACs) are increasingly prescribed for life-long anticoagulation in chronic thromboembolic pulmonary hypertension (CTEPH) patients, despite not being recommended in the guidelines. This study aims to evaluate the efficacy and safety of DOACs in CTEPH patients.

Methods: From May 2013 to December 2022, patients who were first diagnosed with CTEPH in Fuwai Hospital and started long-term anticoagulation treatment with warfarin or DOACs were retrospectively included and followed up until (1) death, (2) transition to other kinds of anticoagulants, or (3) discontinuation of anticoagulation.

208 W single-frequency 1064 nm laser based on a single-crystal fiber master-oscillator power amplifier.

High-power all-solid-state continuous-wave (CW) single-frequency laser with high linear polarization is a significant source for quantum optics and precision measurement. In this Letter, a high-power linearly polarized CW single-frequency laser based on the single-crystal fiber (SCF) master-oscillator power amplifier (MOPA) is presented, in which a homemade 140 W low-noise CW single-frequency laser and a Nd:YAG SCF are firstly employed as the seed laser and the medium of the MOPA, respectively. The mode-matching between the pump laser propagated with waveguide form and the freely propagated seed laser is optimized by considering the influence of the degradations of the polarization and the beam quality.

Self-mode-matching compact low-noise all-solid-state continuous wave single-frequency laser with output power of 140 W.

The high power all-solid-state continuous wave single-frequency laser is a significant source for science and application due to good beam quality and low noise. However, the output power of the laser is usually restricted by the harmful thermal lens effect of the solid gain medium. To address this issue, we develop a self-mode-matching compact all-solid-state laser with a symmetrical ring resonator in which four end-pumped Nd:YVO laser crystals are used for both laser gain media and mode-matching elements.

Functional follow-up after endoscopic calcaneoplasty for Haglund's deformity using the biodex isokinetic muscle testing system: A case series.

Isokinetic muscle strength test implemented by the Biodex system is a method used for evaluating muscle function that has been applied clinically in the field of sports and rehabilitation medicine. However, information on its application on Haglund's deformity remain insufficient. Therefore, the present study examined the effectiveness of the muscle strength test using the Biodex system in evaluating the recovery of athletic capacity in patients with Haglund's deformity following endoscopic surgery.

Self-injection locked CW single-frequency tunable Ti:sapphire laser.

A self-injection locked continuous-wave (CW) single-frequency tunable Ti:sapphire laser is demonstrated in this paper. Unidirectional operation of the presented Ti:sapphire laser is achieved by using a retro-reflecting device which can retro-reflect a seed laser beam from one direction back into the counter-propagating field. On the basis, the influence of the transmission of output coupler on the unidirectional operation is investigated and it is found that stable unidirectional and single-frequency operation of the Ti:sapphire laser is achieved when the loss difference between both output directions is larger than a certain value, which is easy to be realized by choosing the transmission of output coupler.

Single-frequency CW Ti:sapphire laser with intensity noise manipulation and continuous frequency-tuning.

We present a tunable single-frequency CW Ti:sapphire laser with intensity noise manipulation. The manipulation of the laser intensity noise is realized by varying the frequency of the modulation signal loaded on the electrodes of an intracavity electro-optic etalon. A lithium niobate (LiNbO) crystal is used to act as the electro-optic etalon, and its electro-optic effect is utilized to modulate the intracavity laser intensity for locking itself to the oscillating wavelength of the laser to implement continuous frequency-tuning.

Generation of high-power single-frequency 397.5 nm laser with long lifetime and perfect beam quality in an external enhancement-cavity with MgO-doped PPSLT.

Continuous-wave single-frequency high power 397.5 nm laser with long lifetime and perfect beam quality is one of the essential resource to generate the squeezed and entanglement states of optical beams resonant with D line of Rubidium atoms at 795 nm. In this paper, We present the experimental generation of single-frequency high power 397.